Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
2R01GM048036-05
Application #
2185461
Study Section
Special Emphasis Panel (ZRG3-BBCA (01))
Project Start
1992-08-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Privalov, Peter L; Dragan, Anatoly I; Crane-Robinson, Colyn (2009) The cost of DNA bending. Trends Biochem Sci 34:464-70
Crane-Robinson, Colyn; Dragan, Anatoly I; Read, Christopher M (2009) Defining the thermodynamics of protein/DNA complexes and their components using micro-calorimetry. Methods Mol Biol 543:625-51
Dragan, Anatoly I; Privalov, Peter L (2008) Use of fluorescence resonance energy transfer (FRET) in studying protein-induced DNA bending. Methods Enzymol 450:185-99
Privalov, Peter L; Dragan, Anatoly I (2007) Microcalorimetry of biological macromolecules. Biophys Chem 126:16-24
Privalov, Peter L; Dragan, Anatoly I; Crane-Robinson, Colyn et al. (2007) What drives proteins into the major or minor grooves of DNA? J Mol Biol 365:1-9
Crane-Robinson, Colyn; Dragan, Anatoly I; Privalov, Peter L (2006) The extended arms of DNA-binding domains: a tale of tails. Trends Biochem Sci 31:547-52
Dragan, Anatoly I; Li, Zhenlan; Makeyeva, Elena N et al. (2006) Forces driving the binding of homeodomains to DNA. Biochemistry 45:141-51
Hargreaves, Victoria V; Makeyeva, Elena N; Dragan, Anatoly I et al. (2005) Stability and DNA binding ability of the DNA binding domains of interferon regulatory factors 1 and 3. Biochemistry 44:14202-9
Dragan, Anatoly I; Frank, Leslie; Liu, Yingyun et al. (2004) Thermodynamic signature of GCN4-bZIP binding to DNA indicates the role of water in discriminating between the AP-1 and ATF/CREB sites. J Mol Biol 343:865-78
Dragan, Anatoly I; Liu, Yingyun; Makeyeva, Elena N et al. (2004) DNA-binding domain of GCN4 induces bending of both the ATF/CREB and AP-1 binding sites of DNA. Nucleic Acids Res 32:5192-7

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