Genetic Control of Cell Polarity in Budding Yeast - Ira Herskowitz

Abstract

Funding Agency

Agency: National Institute of Health (NIH)
Institute: National Institute of General Medical Sciences (NIGMS)
Type: Research Project (R01)
Project #: 2R01GM048052-05
Application #: 2185484
Study Section: Special Emphasis Panel (ZRG2-GEN (05))

Project Start: 1992-08-01
Project End: 2000-07-31
Budget Start: 1996-08-01
Budget End: 1997-07-31
Support Year: 5
Fiscal Year: 1996
Total Cost
Indirect Cost

Institution

Name: University of California San Francisco
Department: Biochemistry
Type: Schools of Medicine
DUNS #: 073133571

City: San Francisco
State: CA
Country: United States
Zip Code: 94143

Related projects


NIH 1999 R01 GM	Genetic Control of Cell Polarity in Budding Yeast Herskowitz, Ira / University of California San Francisco
NIH 1998 R01 GM	Genetic Control of Cell Polarity in Budding Yeast Herskowitz, Ira / University of California San Francisco
NIH 1997 R01 GM	Genetic Control of Cell Polarity in Budding Yeast Herskowitz, Ira / University of California San Francisco
NIH 1996 R01 GM	Genetic Control of Cell Polarity in Budding Yeast Herskowitz, Ira / University of California San Francisco
NIH 1995 R01 GM	Genetic Control of Cell Polarity in Budding Yeast Herskowitz, Ira / University of California San Francisco
NIH 1994 R01 GM	Genetic Control of Cell Polarity in Budding Yeast Herskowitz, Ira / University of California San Francisco
NIH 1993 R01 GM	Genetic Control of Cell Polarity in Budding Yeast Herskowitz, Ira / University of California San Francisco
NIH 1992 R01 GM	Genetic Control of Cell Polarity in Budding Yeast Herskowitz, Ira / University of California San Francisco

Publications

Kozminski, Keith G; Beven, Laure; Angerman, Elizabeth et al. (2003) Interaction between a Ras and a Rho GTPase couples selection of a growth site to the development of cell polarity in yeast. Mol Biol Cell 14:4958-70

Park, H O; Sanson, A; Herskowitz, I (1999) Localization of Bud2p, a GTPase-activating protein necessary for programming cell polarity in yeast to the presumptive bud site. Genes Dev 13:1912-7

Butty, A C; Pryciak, P M; Huang, L S et al. (1998) The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating. Science 282:1511-6

Park, H O; Bi, E; Pringle, J R et al. (1997) Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity. Proc Natl Acad Sci U S A 94:4463-8

Gray, J V; Ogas, J P; Kamada, Y et al. (1997) A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator. EMBO J 16:4924-37

Leberer, E; Chenevert, J; Leeuw, T et al. (1996) Genetic interactions indicate a role for Mdg1p and the SH3 domain protein Bem1p in linking the G-protein mediated yeast pheromone signalling pathway to regulators of cell polarity. Mol Gen Genet 252:608-21

Chenevert, J; Valtz, N; Herskowitz, I (1994) Identification of genes required for normal pheromone-induced cell polarization in Saccharomyces cerevisiae. Genetics 136:1287-96

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