Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM049119-04
Application #
2186661
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1993-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Biochemistry
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Kadura, Sheila; He, Xiangwei; Vanoosthuyse, Vincent et al. (2005) The A78V mutation in the Mad3-like domain of Schizosaccharomyces pombe Bub1p perturbs nuclear accumulation and kinetochore targeting of Bub1p, Bub3p, and Mad3p and spindle assembly checkpoint function. Mol Biol Cell 16:385-95
Umeda, Makoto; Izaddoost, Shahed; Cushman, Ian et al. (2005) The fission yeast Schizosaccharomyces pombe has two importin-alpha proteins, Imp1p and Cut15p, which have common and unique functions in nucleocytoplasmic transport and cell cycle progression. Genetics 171:7-21
Chang, Fred; Re, Fabio; Sebastian, Sarah et al. (2004) HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes. Mol Biol Cell 15:1793-801
Yoshida, Minoru; Sazer, Shelley (2004) Nucleocytoplasmic transport and nuclear envelope integrity in the fission yeast Schizosaccharomyces pombe. Methods 33:226-38
Bai, Siau Wei; Rouquette, Jacques; Umeda, Makoto et al. (2004) The fission yeast Nup107-120 complex functionally interacts with the small GTPase Ran/Spi1 and is required for mRNA export, nuclear pore distribution, and proper cell division. Mol Cell Biol 24:6379-92
Salus, Sandra S; Demeter, Janos; Sazer, Shelley (2002) The Ran GTPase system in fission yeast affects microtubules and cytokinesis in cells that are competent for nucleocytoplasmic protein transport. Mol Cell Biol 22:8491-505
Matynia, Anna; Salus, Sandra S; Sazer, Shelley (2002) Three proteins required for early steps in the protein secretory pathway also affect nuclear envelope structure and cell cycle progression in fission yeast. J Cell Sci 115:421-31
Fleig, U; Salus, S S; Karig, I et al. (2000) The fission yeast ran GTPase is required for microtubule integrity. J Cell Biol 151:1101-11
He, X; Jones, M H; Winey, M et al. (1998) Mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe. J Cell Sci 111 ( Pt 12):1635-47
Demeter, J; Sazer, S (1998) imp2, a new component of the actin ring in the fission yeast Schizosaccharomyces pombe. J Cell Biol 143:415-27

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