Ras-Related Protein in Differentiating Mel Cells

Boss, Gerry R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM049360-04
• Application #: 2186952
• Study Section: Hematology Subcommittee 2 (HEM)
• Project Start: 1993-05-01
• Project End: 1997-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 4
• Fiscal Year: 1996

Institution

• Name: University of California San Diego
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 077758407
• City: La Jolla
• State: CA
• Country: United States
• Zip Code: 92093

Publications

Pilz, R B; Huvar, I; Scheele, J S et al. (1997) A decrease in the intracellular guanosine 5'-triphosphate concentration is necessary for granulocytic differentiation of HL-60 cells, but growth cessation and differentiation are not associated with a change in the activation state of Ras, the transformin Cell Growth Differ 8:53-9

Suhasini, M; Boss, G R; Pascual, F E et al. (1995) Nitric oxide-releasing agents and cGMP analogues inhibit murine erythroleukemia cell differentiation and suppress erythroid-specific gene expression: correlation with decreased DNA binding of NF-E2 and altered c-myb mRNA expression. Cell Growth Differ 6:1559-66

Pilz, R B; Berjis, M; Idriss, S D et al. (1994) Isolation and characterization of HL-60 cells resistant to nitroprusside-induced differentiation. J Biol Chem 269:32155-61

Scheele, J S; Pilz, R B; Quilliam, L A et al. (1994) Identification of a ras-related protein in murine erythroleukemia cells that is a cAMP-dependent protein kinase substrate and is phosphorylated during chemically induced differentiation. J Biol Chem 269:18599-606