Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050209-03
Application #
2187881
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1994-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Contestabile, R; Angelaccio, S; Bossa, F et al. (2000) Role of tyrosine 65 in the mechanism of serine hydroxymethyltransferase. Biochemistry 39:7492-500
Scarsdale, J N; Radaev, S; Kazanina, G et al. (2000) Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate. J Mol Biol 296:155-68
Scarsdale, J N; Kazanina, G; Radaev, S et al. (1999) Crystal structure of rabbit cytosolic serine hydroxymethyltransferase at 2.8 A resolution: mechanistic implications. Biochemistry 38:8347-58
Kazanina, G; Radaev, S; Wright, H T et al. (1998) Crystal forms and subunit stoichiometry of serine hydroxymethyltransferase. J Struct Biol 123:169-74