Combinatorial Strategies Applied to Organic Compounds

Agency: National Institute of Health (NIH)
Institute: National Institute of General Medical Sciences (NIGMS)
Type: Research Project (R01)
Project #: 5R01GM050353-03
Application #: 2188132
Study Section: Bio-Organic and Natural Products Chemistry Study Section (BNP)


NIH 2004 R01 GM	Combinatorial Target-Guided Ligand Assembly Ellman, Jonathan A. / University of California Berkeley	$206,266
NIH 2003 R01 GM	Combinatorial Target-Guided Ligand Assembly Ellman, Jonathan A. / University of California Berkeley	$206,266
NIH 2002 R01 GM	Combinatorial Target-Guided Ligand Assembly Ellman, Jonathan A. / University of California Berkeley	$206,266
NIH 2001 R01 GM	Combinatorial Target-Guided Ligand Assembly Ellman, Jonathan A. / University of California Berkeley	$229,120
NIH 2000 R01 GM	Privileged Structure Libraries Ellman, Jonathan A. / University of California Berkeley	$171,581
NIH 1999 R01 GM	Privileged Structure Libraries Ellman, Jonathan A. / University of California Berkeley
NIH 1998 R01 GM	Privileged Structure Libraries Ellman, Jonathan A. / University of California Berkeley
NIH 1996 R01 GM	Combinatorial Strategies Applied to Organic Compounds Ellman, Jonathan A. / University of California Berkeley
NIH 1995 R01 GM	Combinatorial Strategies Applied to Organic Compounds Ellman, Jonathan A. / University of California Berkeley
NIH 1994 R01 GM	Combinatorial Strategies Applied to Organic Compounds Ellman, Jonathan A. / University of California Berkeley

Tan, Kian L; Vasudevan, Anil; Bergman, Robert G et al. (2003) Microwave-assisted C-H bond activation: a rapid entry into functionalized heterocycles. Org Lett 5:2131-4

Boitano, Anthony; Ellman, Jonathan A; Glick, Gary D et al. (2003) The proapoptotic benzodiazepine Bz-423 affects the growth and survival of malignant B cells. Cancer Res 63:6870-6

Ahrendt, Kateri A; Bergman, Robert G; Ellman, Jonathan A (2003) Synthesis of a tricyclic mescaline analogue by catalytic C-H bond activation. Org Lett 5:1301-3

Boitano, Anthony; Emal, Cory D; Leonetti, Francesco et al. (2003) Structure activity studies of a novel cytotoxic benzodiazepine. Bioorg Med Chem Lett 13:3327-30

Bednarski, Jeffrey J; Warner, Roscoe E; Rao, Tharaknath et al. (2003) Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine. Arthritis Rheum 48:757-66

Blatt, Neal B; Bednarski, Jeffrey J; Warner, Roscoe E et al. (2002) Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility. J Clin Invest 110:1123-32

Wang, Xueqing; Choe, Youngchool; Craik, Charles S et al. (2002) Design and synthesis of novel inhibitors of gelatinase B. Bioorg Med Chem Lett 12:2201-4

Kehoe, John W; Maly, Dustin J; Verdugo, Dawn E et al. (2002) Tyrosylprotein sulfotransferase inhibitors generated by combinatorial target-guided ligand assembly. Bioorg Med Chem Lett 12:329-32

Thalji, R K; Ahrendt, K A; Bergman, R G et al. (2001) Annulation of aromatic imines via directed C-H activation with Wilkinson's catalyst. J Am Chem Soc 123:9692-3

Showing the most recent 10 out of 12 publications