Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050624-06
Application #
2188589
Study Section
Physiology Study Section (PHY)
Project Start
1990-04-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
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Grant, G A; Al-Rabiee, R; Xu, X L et al. (1997) Critical interactions at the dimer interface of kappa-bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist. Biochemistry 36:3353-8
Chiappinelli, V A; Weaver, W R; McLane, K E et al. (1996) Binding of native kappa-neurotoxins and site-directed mutants to nicotinic acetylcholine receptors. Toxicon 34:1243-56
Fiordalisi, J J; James, P L; Zhang, Y et al. (1996) Facile production of native-like kappa-bungarotoxin in yeast: an enhanced system for the production of a neuronal nicotinic acetylcholine receptor probe. Toxicon 34:213-24
Fiordalisi, J J; al-Rabiee, R; Chiappinelli, V A et al. (1994) Site-directed mutagenesis of kappa-bungarotoxin: implications for neuronal receptor specificity. Biochemistry 33:3872-7
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Fiordalisi, J J; al-Rabiee, R; Chiappinelli, V A et al. (1994) Affinity of native kappa-bungarotoxin and site-directed mutants for the muscle nicotinic acetylcholine receptor. Biochemistry 33:12962-7