Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM050839-02
Application #
2188962
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1995-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Utah
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112

  Publications

Gao, Song-Qi; Sun, Yongen; Kopecková, Pavla et al. (2009) Antitumor efficacy of colon-specific HPMA copolymer/9-aminocamptothecin conjugates in mice bearing human-colon carcinoma xenografts. Macromol Biosci 9:1135-42
Gao, Song-Qi; Sun, Yongen; Kopeckova, Pavla et al. (2008) Pharmacokinetic modeling of absorption behavior of 9-aminocamptothecin (9-AC) released from colon-specific HPMA copolymer-9-AC conjugate in rats. Pharm Res 25:218-26
Gao, Song-Qi; Lu, Zheng-Rong; Kopeckova, Pavla et al. (2007) Biodistribution and pharmacokinetics of colon-specific HPMA copolymer--9-aminocamptothecin conjugate in mice. J Control Release 117:179-85
Lu, R H; Kopeckova, P; Kopecek, J (1999) Degradation and aggregation of human calcitonin in vitro. Pharm Res 16:359-67
Akala, E O; Kopeckova, P; Kopecek, J (1998) Novel pH-sensitive hydrogels with adjustable swelling kinetics. Biomaterials 19:1037-47
Ghandehari, H; Smith, P L; Ellens, H et al. (1997) Size-dependent permeability of hydrophilic probes across rabbit colonic epithelium. J Pharmacol Exp Ther 280:747-53