Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM051661-13
Application #
2190338
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1980-09-30
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
13
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Tufts University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Schneiders, Thamarai; Barbosa, Teresa M; McMurry, Laura M et al. (2004) The Escherichia coli transcriptional regulator MarA directly represses transcription of purA and hdeA. J Biol Chem 279:9037-42
Bina, Xiaowen; Perreten, Vincent; Levy, Stuart B (2003) The periplasmic protein MppA requires an additional mutated locus to repress marA expression in Escherichia coli. J Bacteriol 185:1465-9
Schneiders, T; Amyes, S G B; Levy, S B (2003) Role of AcrR and ramA in fluoroquinolone resistance in clinical Klebsiella pneumoniae isolates from Singapore. Antimicrob Agents Chemother 47:2831-7
Koutsolioutsou, A; Martins, E A; White, D G et al. (2001) A soxRS-constitutive mutation contributing to antibiotic resistance in a clinical isolate of Salmonella enterica (Serovar typhimurium). Antimicrob Agents Chemother 45:38-43
Perreten, V; Schwarz, F V; Teuber, M et al. (2001) Mdt(A), a new efflux protein conferring multiple antibiotic resistance in Lactococcus lactis and Escherichia coli. Antimicrob Agents Chemother 45:1109-14
Wang, H; Dzink-Fox, J L; Chen, M et al. (2001) Genetic characterization of highly fluoroquinolone-resistant clinical Escherichia coli strains from China: role of acrR mutations. Antimicrob Agents Chemother 45:1515-21
Alekshun, M N; Kim, Y S; Levy, S B (2000) Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding. Mol Microbiol 35:1394-404
Oethinger, M; Kern, W V; Jellen-Ritter, A S et al. (2000) Ineffectiveness of topoisomerase mutations in mediating clinically significant fluoroquinolone resistance in Escherichia coli in the absence of the AcrAB efflux pump. Antimicrob Agents Chemother 44:3-Oct
Kern, W V; Oethinger, M; Jellen-Ritter, A S et al. (2000) Non-target gene mutations in the development of fluoroquinolone resistance in Escherichia coli. Antimicrob Agents Chemother 44:814-20
Barbosa, T M; Levy, S B (2000) Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA. J Bacteriol 182:3467-74

Showing the most recent 10 out of 23 publications