Anesthetic Mechanisms in GABA - R Gene Targeted Mice

Firestone, Leonard L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM052035-03
• Application #: 2190902
• Study Section: Surgery, Anesthesiology and Trauma Study Section (SAT)
• Project Start: 1995-01-01
• Project End: 1998-08-31
• Budget Start: 1996-09-01
• Budget End: 1997-08-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of Pittsburgh
• Department: Anesthesiology
• Type: Schools of Medicine
• DUNS #: 053785812
• City: Pittsburgh
• State: PA
• Country: United States
• Zip Code: 15213

Publications

June Sr, Harry L; Foster, Katrina L; Eiler 2nd, William J A et al. (2007) Dopamine and benzodiazepine-dependent mechanisms regulate the EtOH-enhanced locomotor stimulation in the GABAA alpha1 subunit null mutant mice. Neuropsychopharmacology 32:137-52

Ferguson, Carolyn; Hardy, Steven L; Werner, David F et al. (2007) New insight into the role of the beta3 subunit of the GABAA-R in development, behavior, body weight regulation, and anesthesia revealed by conditional gene knockout. BMC Neurosci 8:85

Sonner, James M; Cascio, Mike; Xing, Yilei et al. (2005) Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear. Mol Pharmacol 68:61-8

Chandra, Dev; Korpi, Esa R; Miralles, Celia P et al. (2005) GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines. BMC Neurosci 6:30