Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052201-02
Application #
2022992
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1995-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Boston University
Department
Type
Organized Research Units
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118

  Publications

Kuhn, H; Demidov, V V; Nielsen, P E et al. (1999) An experimental study of mechanism and specificity of peptide nucleic acid (PNA) binding to duplex DNA. J Mol Biol 286:1337-45
Bukanov, N O; Demidov, V V; Nielsen, P E et al. (1998) PD-loop: a complex of duplex DNA with an oligonucleotide. Proc Natl Acad Sci U S A 95:5516-20
Lomakin, A; Frank-Kamenetskii, M D (1998) A theoretical analysis of specificity of nucleic acid interactions with oligonucleotides and peptide nucleic acids (PNAs). J Mol Biol 276:57-70
Kuhn, H; Demidov, V V; Frank-Kamenetskii, M D et al. (1998) Kinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA. Nucleic Acids Res 26:582-7
Demidov, V V; Yavnilovich, M V; Frank-Kamenetskii, M D (1997) Kinetic analysis of specificity of duplex DNA targeting by homopyrimidine peptide nucleic acids. Biophys J 72:2763-9