Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM052216-06
Application #
6180610
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Program Officer
Chin, Jean
Project Start
1995-04-01
Project End
2003-07-31
Budget Start
2000-08-01
Budget End
2001-07-31
Support Year
6
Fiscal Year
2000
Total Cost
$204,606
Indirect Cost
Name
Wayne State University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Chen, Jian; Li, Jiaojiao; Jiang, Xuan et al. (2017) Conserved cysteine residues determine substrate specificity in a novel As(III) S-adenosylmethionine methyltransferase from Aspergillus fumigatus. Mol Microbiol 104:250-259
Chen, Jian; Nadar, Venkadesh Sarkarai; Rosen, Barry P (2017) A novel MAs(III)-selective ArsR transcriptional repressor. Mol Microbiol 106:469-478
Chen, Jian; Bhattacharjee, Hiranmoy; Rosen, Barry P (2015) ArsH is an organoarsenical oxidase that confers resistance to trivalent forms of the herbicide monosodium methylarsenate and the poultry growth promoter roxarsone. Mol Microbiol 96:1042-52
Rosen, Barry P; Liu, Zijuan (2009) Transport pathways for arsenic and selenium: a minireview. Environ Int 35:512-5
Mukhopadhyay, Rita; Bisacchi, Davide; Zhou, Yao et al. (2009) Structural characterization of the As/Sb reductase LmACR2 from Leishmania major. J Mol Biol 386:1229-39
Bhattacharjee, Hiranmoy; Rosen, Barry P; Mukhopadhyay, Rita (2009) Aquaglyceroporins and metalloid transport: implications in human diseases. Handb Exp Pharmacol :309-25
Sundaram, Sabarinath; Rathinasabapathi, Bala; Ma, Lena Q et al. (2008) An arsenate-activated glutaredoxin from the arsenic hyperaccumulator fern Pteris vittata L. regulates intracellular arsenite. J Biol Chem 283:6095-101
Duan, Gui-Lan; Zhou, Yao; Tong, Yi-Ping et al. (2007) A CDC25 homologue from rice functions as an arsenate reductase. New Phytol 174:311-21
Zhou, Yao; Bhattacharjee, Hiranmoy; Mukhopadhyay, Rita (2006) Bifunctional role of the leishmanial antimonate reductase LmACR2 as a protein tyrosine phosphatase. Mol Biochem Parasitol 148:161-8
Bisacchi, Davide; Zhou, Yao; Rosen, Barry P et al. (2006) Crystallization and preliminary crystallographic characterization of LmACR2, an arsenate/antimonate reductase from Leishmania major. Acta Crystallogr Sect F Struct Biol Cryst Commun 62:976-9

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