Protein Kinase-Mediated Regulation of Mrna Turnover

Jungmann, Richard A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 1R01GM053115-01A1
• Application #: 2192396
• Study Section: Biochemical Endocrinology Study Section (BCE)
• Project Start: 1996-05-01
• Project End: 1999-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Northwestern University at Chicago
• Department: Anatomy/Cell Biology
• Type: Schools of Dentistry
• DUNS #: 005436803
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60611

Publications

Jungmann, Richard A; Kiryukhina, Olga (2005) Cyclic AMP and AKAP-mediated targeting of protein kinase A regulates lactate dehydrogenase subunit A mRNA stability. J Biol Chem 280:25170-7

Short, S; Tian, D; Short, M L et al. (2000) Structural determinants for post-transcriptional stabilization of lactate dehydrogenase A mRNA by the protein kinase C signal pathway. J Biol Chem 275:12963-9

Tian, D; Huang, D; Brown, R C et al. (1998) Protein kinase A stimulates binding of multiple proteins to a U-rich domain in the 3'-untranslated region of lactate dehydrogenase A mRNA that is required for the regulation of mRNA stability. J Biol Chem 273:28454-60

Tian, D; Huang, D; Short, S et al. (1998) Protein kinase A-regulated instability site in the 3'-untranslated region of lactate dehydrogenase-A subunit mRNA. J Biol Chem 273:24861-6

Jungmann, R A; Huang, D; Tian, D (1998) Regulation of LDH-A gene expression by transcriptional and posttranscriptional signal transduction mechanisms. J Exp Zool 282:188-95