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Gaynor, Marne; Mankin, Alexander S (2003) Macrolide antibiotics: binding site, mechanism of action, resistance. Curr Top Med Chem 3:949-61
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Garza-Ramos, G; Xiong, L; Zhong, P et al. (2001) Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA. J Bacteriol 183:6898-907
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Tenson, T; Mankin, A S (2001) Short peptides conferring resistance to macrolide antibiotics. Peptides 22:1661-8
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Belova, L; Tenson, T; Xiong, L et al. (2001) A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit. Proc Natl Acad Sci U S A 98:3726-31
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Velichutina, I V; Dresios, J; Hong, J Y et al. (2000) Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome. RNA 6:1174-84
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Xiong, L; Kloss, P; Douthwaite, S et al. (2000) Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action. J Bacteriol 182:5325-31
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Khaitovich, P; Mankin, A S (1999) Effect of antibiotics on large ribosomal subunit assembly reveals possible function of 5 S rRNA. J Mol Biol 291:1025-34
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Khaitovich, P; Mankin, A S; Green, R et al. (1999) Characterization of functionally active subribosomal particles from Thermus aquaticus. Proc Natl Acad Sci U S A 96:85-90
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Khaitovich, P; Tenson, T; Kloss, P et al. (1999) Reconstitution of functionally active Thermus aquaticus large ribosomal subunits with in vitro-transcribed rRNA. Biochemistry 38:1780-8
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Porse, B T; Leviev, I; Mankin, A S et al. (1998) The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre. J Mol Biol 276:391-404
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