Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054098-01
Application #
2193494
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1996-05-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Suny Downstate Medical Center
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
068552207
City
Brooklyn
State
NY
Country
United States
Zip Code
11203
Stepanova, Ekaterina; Wang, Minshi; Severinov, Konstantin et al. (2009) Early transcriptional arrest at Escherichia coli rplN and ompX promoters. J Biol Chem 284:35702-13
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Laptenko, Oleg; Kim, Seung-Sup; Lee, Jookyung et al. (2006) pH-dependent conformational switch activates the inhibitor of transcription elongation. EMBO J 25:2131-41
Tuske, Steven; Sarafianos, Stefan G; Wang, Xinyue et al. (2005) Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation. Cell 122:541-52
Adelman, Karen; Yuzenkova, Julia; La Porta, Arthur et al. (2004) Molecular mechanism of transcription inhibition by peptide antibiotic Microcin J25. Mol Cell 14:753-62
Epshtein, Vitaly; Toulme, Francine; Rahmouni, A Rachid et al. (2003) Transcription through the roadblocks: the role of RNA polymerase cooperation. EMBO J 22:4719-27

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