Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM054510-09
Application #
6386347
Study Section
Genetics Study Section (GEN)
Program Officer
Greenberg, Judith H
Project Start
1992-08-01
Project End
2004-03-31
Budget Start
2001-04-01
Budget End
2002-03-31
Support Year
9
Fiscal Year
2001
Total Cost
$293,259
Indirect Cost
Name
Columbia University (N.Y.)
Department
Biochemistry
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Zeiske, Tim; Baburajendran, Nithya; Kaczynska, Anna et al. (2018) Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep 24:2221-2230
Kribelbauer, Judith F; Laptenko, Oleg; Chen, Siying et al. (2017) Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes. Cell Rep 19:2383-2395
Merabet, Samir; Mann, Richard S (2016) To Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins. Trends Genet 32:334-347
Zhou, Tianyin; Shen, Ning; Yang, Lin et al. (2015) Quantitative modeling of transcription factor binding specificities using DNA shape. Proc Natl Acad Sci U S A 112:4654-9
O'Connell, Nichole E; Lelli, Katherine; Mann, Richard S et al. (2015) Asparagine deamidation reduces DNA-binding affinity of the Drosophila melanogaster Scr homeodomain. FEBS Lett 589:3237-41
Abe, Namiko; Dror, Iris; Yang, Lin et al. (2015) Deconvolving the recognition of DNA shape from sequence. Cell 161:307-18
Crocker, Justin; Abe, Namiko; Rinaldi, Lucrezia et al. (2015) Low affinity binding site clusters confer hox specificity and regulatory robustness. Cell 160:191-203
Riley, Todd R; Slattery, Matthew; Abe, Namiko et al. (2014) SELEX-seq: a method for characterizing the complete repertoire of binding site preferences for transcription factor complexes. Methods Mol Biol 1196:255-78
Agelopoulos, Marios; McKay, Daniel J; Mann, Richard S (2014) cgChIP: a cell type- and gene-specific method for chromatin analysis. Methods Mol Biol 1196:291-306
Shazman, Shula; Lee, Hunjoong; Socol, Yakov et al. (2014) OnTheFly: a database of Drosophila melanogaster transcription factors and their binding sites. Nucleic Acids Res 42:D167-71

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