Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054594-01
Application #
2193943
Study Section
Special Emphasis Panel (ZRG2-GEN (05))
Project Start
1996-08-01
Project End
2001-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rutgers University
Department
Type
Organized Research Units
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Xu, Aiguo; Haines, Nicola; Dlugosz, Malgosia et al. (2007) In vitro reconstitution of the modulation of Drosophila Notch-ligand binding by Fringe. J Biol Chem 282:35153-62
Major, Robert J; Irvine, Kenneth D (2006) Localization and requirement for Myosin II at the dorsal-ventral compartment boundary of the Drosophila wing. Dev Dyn 235:3051-8
Haines, Nicola; Irvine, Kenneth D (2005) Functional analysis of Drosophila beta1,4-N-acetlygalactosaminyltransferases. Glycobiology 15:335-46
Okajima, Tetsuya; Xu, Aiguo; Lei, Liang et al. (2005) Chaperone activity of protein O-fucosyltransferase 1 promotes notch receptor folding. Science 307:1599-603
Major, Robert J; Irvine, Kenneth D (2005) Influence of Notch on dorsoventral compartmentalization and actin organization in the Drosophila wing. Development 132:3823-33
Xu, Aiguo; Lei, Liang; Irvine, Kenneth D (2005) Regions of Drosophila Notch that contribute to ligand binding and the modulatory influence of Fringe. J Biol Chem 280:30158-65
Koles, Kate; Irvine, Kenneth D; Panin, Vladislav M (2004) Functional characterization of Drosophila sialyltransferase. J Biol Chem 279:4346-57
Correia, Trudy; Papayannopoulos, Venizelos; Panin, Vladislav et al. (2003) Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila. Proc Natl Acad Sci U S A 100:6404-9
Li, Yanxia; Lei, Liang; Irvine, Kenneth D et al. (2003) Notch activity in neural cells triggered by a mutant allele with altered glycosylation. Development 130:2829-40
Lei, Liang; Xu, Aiguo; Panin, Vladislav M et al. (2003) An O-fucose site in the ligand binding domain inhibits Notch activation. Development 130:6411-21

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