Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054706-01
Application #
2194043
Study Section
Special Emphasis Panel (ZRG2-ALY (01))
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Agarwal, Pujya; Raghavan, Arvind; Nandiwada, Sarada L et al. (2009) Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory. J Immunol 183:1695-704
Zhang, Ruan; Zhang, Na; Mueller, Daniel L (2008) Casitas B-lineage lymphoma b inhibits antigen recognition and slows cell cycle progression at late times during CD4+ T cell clonal expansion. J Immunol 181:5331-9
Mondino, Anna; Mueller, Daniel L (2007) mTOR at the crossroads of T cell proliferation and tolerance. Semin Immunol 19:162-72
Bonnevier, Jody L; Yarke, Cory A; Mueller, Daniel L (2006) Sustained B7/CD28 interactions and resultant phosphatidylinositol 3-kinase activity maintain G1-->S phase transitions at an optimal rate. Eur J Immunol 36:1583-97
Nandiwada, Sarada L; Li, Wei; Zhang, Ruan et al. (2006) p300/Cyclic AMP-responsive element binding-binding protein mediates transcriptional coactivation by the CD28 T cell costimulatory receptor. J Immunol 177:401-13
Vanasek, Tracy L; Nandiwada, Sarada L; Jenkins, Marc K et al. (2006) CD25+Foxp3+ regulatory T cells facilitate CD4+ T cell clonal anergy induction during the recovery from lymphopenia. J Immunol 176:5880-9
Bonnevier, Jody L; Zhang, Ruan; Mueller, Daniel L (2005) E3 ubiquitin ligases and their control of T cell autoreactivity. Arthritis Res Ther 7:233-42
Mueller, Daniel L (2004) E3 ubiquitin ligases as T cell anergy factors. Nat Immunol 5:883-90
Bonnevier, Jody L; Mueller, Daniel L (2002) Cutting edge: B7/CD28 interactions regulate cell cycle progression independent of the strength of TCR signaling. J Immunol 169:6659-63
Li, W; Whaley, C D; Bonnevier, J L et al. (2001) CD28 signaling augments Elk-1-dependent transcription at the c-fos gene during antigen stimulation. J Immunol 167:827-35

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