Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
1R01GM054739-01
Application #
2194072
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1996-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Pathology
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Shao, Hanshuang; Yi, Xiao-Ming; Wells, Alan (2008) Epidermal growth factor protects fibroblasts from apoptosis via PI3 kinase and Rac signaling pathways. Wound Repair Regen 16:551-8
Allen, Fred D; Asnes, Clara F; Chang, Philip et al. (2002) Epidermal growth factor induces acute matrix contraction and subsequent calpain-modulated relaxation. Wound Repair Regen 10:67-76
Glading, A; Uberall, F; Keyse, S M et al. (2001) Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling. J Biol Chem 276:23341-8
Narang, A; Subramanian, K K; Lauffenburger, D A (2001) A mathematical model for chemoattractant gradient sensing based on receptor-regulated membrane phospholipid signaling dynamics. Ann Biomed Eng 29:677-91
Glading, A; Chang, P; Lauffenburger, D A et al. (2000) Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway. J Biol Chem 275:2390-8
Shiraha, H; Gupta, K; Drabik, K et al. (2000) Aging fibroblasts present reduced epidermal growth factor (EGF) responsiveness due to preferential loss of EGF receptors. J Biol Chem 275:19343-51
Shiraha, H; Glading, A; Gupta, K et al. (1999) IP-10 inhibits epidermal growth factor-induced motility by decreasing epidermal growth factor receptor-mediated calpain activity. J Cell Biol 146:243-54
Qin, H; Moellinger, J D; Wells, A et al. (1998) Transcriptional suppression of matrix metalloproteinase-2 gene expression in human astroglioma cells by TNF-alpha and IFN-gamma. J Immunol 161:6664-73
Xie, H; Pallero, M A; Gupta, K et al. (1998) EGF receptor regulation of cell motility: EGF induces disassembly of focal adhesions independently of the motility-associated PLCgamma signaling pathway. J Cell Sci 111 ( Pt 5):615-24
Hardy, R W; Wickramasinghe, N S; Ke, S C et al. (1997) Fatty acids and breast cancer cell proliferation. Adv Exp Med Biol 422:57-69

Showing the most recent 10 out of 13 publications