Specific aims are: (1) to mutagenize kinesin like protein 67A (KLP671A) both in vitro and in vivo to acquire a series of alleles of varying strength; (2) to examine the cellular consequences of detaching mitochondria from the cytoskeleton during oogenesis and early embryogenesis; and (3) to identify genes which interact with KLP67A.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM055103-04
Application #
6386645
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Program Officer
Deatherage, James F
Project Start
1998-05-01
Project End
2003-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
4
Fiscal Year
2001
Total Cost
$181,577
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Genetics
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655