Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM055237-02
Application #
2655026
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1997-02-01
Project End
2001-01-31
Budget Start
1998-02-01
Budget End
1999-01-31
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Pharmacology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611

  Publications

Egli, Martin; Pallan, Pradeep S (2016) Generating Crystallographic Models of DNA Dodecamers from Structures of RNase H:DNA Complexes. Methods Mol Biol 1320:111-26
Mutisya, Daniel; Selvam, Chelliah; Lunstad, Benjamin D et al. (2014) Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs. Nucleic Acids Res 42:6542-51
Kowal, Ewa A; Lad, Rahul R; Pallan, Pradeep S et al. (2013) Recognition of O6-benzyl-2'-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction. Nucleic Acids Res 41:7566-76
Ketkar, Amit; Zafar, Maroof K; Maddukuri, Leena et al. (2013) Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity. Chem Res Toxicol 26:221-32
Seth, Punit P; Pallan, Pradeep S; Swayze, Eric E et al. (2013) Synthesis, duplex stabilization and structural properties of a fluorinated carbocyclic LNA analogue. Chembiochem 14:58-62
Ketkar, Amit; Zafar, Maroof K; Banerjee, Surajit et al. (2012) Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues. Biochemistry 51:9234-44
Patra, Amritraj; Paolillo, Michael; Charisse, Klaus et al. (2012) 2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data. Angew Chem Int Ed Engl 51:11863-6
Pallan, Pradeep S; Allerson, Charles R; Berdeja, Andres et al. (2012) Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs. Chem Commun (Camb) 48:8195-7
Egli, Martin (2012) The steric hypothesis for DNA replication and fluorine hydrogen bonding revisited in light of structural data. Acc Chem Res 45:1237-46
Ketkar, Amit; Zafar, Maroof K; Banerjee, Surajit et al. (2012) A nucleotide-analogue-induced gain of function corrects the error-prone nature of human DNA polymerase iota. J Am Chem Soc 134:10698-705

Showing the most recent 10 out of 45 publications