Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM056271-02
Application #
6041097
Study Section
Project Start
1999-05-01
Project End
2001-04-30
Budget Start
1999-05-01
Budget End
2000-04-30
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Gawley, Robert E (2010) Overview of Carbanion Dynamics and Electrophilic Substitutions in Chiral Organolithium Compounds. Top Stereochem 26:93-133
Gawley, Robert E; Moon, Kwangyul (2007) Stereoselective [2,3]-sigmatropic rearrangements of unstabilized nitrogen ylides. Org Lett 9:3093-6
Klein, Rosalyn; Gawley, Robert E (2007) Configurational and conformational effects on tin-lithium exchange in alpha-aminoorganostannanes by rapid-injection NMR. J Am Chem Soc 129:4126-7
Gawley, Robert E (2006) Do the terms ""% ee"" and ""% de"" make sense as expressions of stereoisomer composition or stereoselectivity? J Org Chem 71:2411-6
Madan, Sachin; Milano, Peter; Eddings, Daniel B et al. (2005) Conversion of five-, six-, and seven-membered lactams to racemic or scalemic 2-substituted heterocycles by amidoalkylation. J Org Chem 70:3066-71
Gawley, Robert E; Dukh, Mykhaylo; Cardona, Claudia M et al. (2005) Heptapeptide mimic of ohmefentanyl binding in the discontinuous mu-opiod receptor. Org Lett 7:2953-6
Santiago, Marcelina; Low, Eddy; Chambournier, Gilles et al. (2003) Modeling and experiment reveal an unexpected stereoelectronic effect on conformation and scalar couplings of alpha-aminoorganostannanes, with possible relevance to the tin-lithium exchange reaction. J Org Chem 68:8480-4
Iula, D M; Gawley, R E (2000) Synthesis and reactivity of dipole-stabilized but unchelated alpha-aminoorganolithiums. J Org Chem 65:6196-201
Chambournier, G; Gawley, R E (2000) Synthesis and reactivity of conformationally locked alpha-aminoorganostannanes and alpha-aminoorganolithiums. Discovery of a surprising configurational requirement for transmetalation. Org Lett 2:1561-4
Gawley, R E; Low, E; Chambournier, G (1999) Unusual conformational effect in alpha-aminoorganostannanes. Org Lett 1:653-5