Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM056445-03
Application #
2857304
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1997-01-01
Project End
2000-12-31
Budget Start
1999-01-01
Budget End
1999-12-31
Support Year
3
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697
Pathuri, Puja; Vogeley, Lutz; Luecke, Hartmut (2008) Crystal structure of metastasis-associated protein S100A4 in the active calcium-bound form. J Mol Biol 383:62-77
Luecke, Hartmut; Schobert, Brigitte; Stagno, Jason et al. (2008) Crystallographic structure of xanthorhodopsin, the light-driven proton pump with a dual chromophore. Proc Natl Acad Sci U S A 105:16561-5
Pathuri, Puja; Nguyen, Emily Tam; Svard, Staffan G et al. (2007) Apo and calcium-bound crystal structures of Alpha-11 giardin, an unusual annexin from Giardia lamblia. J Mol Biol 368:493-508
Stagno, Jason; Aphasizheva, Inna; Aphasizhev, Ruslan et al. (2007) Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc Natl Acad Sci U S A 104:14634-9
Stagno, Jason; Aphasizheva, Inna; Rosengarth, Anja et al. (2007) UTP-bound and Apo structures of a minimal RNA uridylyltransferase. J Mol Biol 366:882-99
Trakhanov, Sergei; Vyas, Nand K; Luecke, Hartmut et al. (2005) Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity. Biochemistry 44:6597-608
Freites, J Alfredo; Ali, Shahla; Rosengarth, Anja et al. (2004) Annexin A1 interaction with a zwitterionic phospholipid monolayer: a fluorescence microscopy study. Langmuir 20:11674-83
Rosengarth, Anja; Luecke, Hartmut (2003) A calcium-driven conformational switch of the N-terminal and core domains of annexin A1. J Mol Biol 326:1317-25
Prosise, Glen L; Luecke, Hartmut (2003) Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism. J Mol Biol 326:517-27
Tran, Jacqueline T; Rosengarth, Anja; Luecke, Hartmut (2002) Cloning, purification and crystallization of full-length human annexin 2. Acta Crystallogr D Biol Crystallogr 58:1854-7

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