Poly (Adp Ribose) Synthetase and Peroxynitrite Induced C

Szabo, Csaba

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Research Project (R01)
• Project #: 5R01GM060915-02
• Application #: 6181517
• Study Section: Surgery, Anesthesiology and Trauma Study Section (SAT)
• Program Officer: Somers, Scott D
• Project Start: 1999-07-01
• Project End: 2003-06-30
• Budget Start: 2000-07-01
• Budget End: 2001-06-30
• Support Year: 2
• Fiscal Year: 2000
• Total Cost: $213,829

Institution

• Name: Inotek Pharmaceuticals Corporation
• City: Beverly
• State: MA
• Country: United States
• Zip Code: 01915

Publications

Gao, Xin; Brown, Gregory K; Elliott, Michael R (2014) Joint modeling compliance and outcome for causal analysis in longitudinal studies. Stat Med 33:3453-65

Maybauer, Marc O; Maybauer, Dirk M; Fraser, John F et al. (2012) Combined recombinant human activated protein C and ceftazidime prevent the onset of acute respiratory distress syndrome in severe sepsis. Shock 37:170-6

Módis, Katalin; Gero, Domokos; Erdélyi, Katalin et al. (2012) Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress. Biochem Pharmacol 83:633-43

Spokas, Megan; Wenzel, Amy; Brown, Gregory K et al. (2012) Characteristics of individuals who make impulsive suicide attempts. J Affect Disord 136:1121-5

Szoleczky, Petra; Módis, Katalin; Nagy, Nóra et al. (2012) Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia. Arch Biochem Biophys 517:53-70

Lange, Matthias; Szabo, Csaba; Traber, Daniel L et al. (2012) Time profile of oxidative stress and neutrophil activation in ovine acute lung injury and sepsis. Shock 37:468-72

Oláh, Gábor; Finnerty, Celeste C; Sbrana, Elena et al. (2011) Increased poly(ADP-ribosyl)ation in skeletal muscle tissue of pediatric patients with severe burn injury: prevention by propranolol treatment. Shock 36:18-23

Bartha, Eva; Asmussen, Sven; Olah, Gabor et al. (2011) Burn and smoke injury activates poly(ADP-ribose)polymerase in circulating leukocytes. Shock 36:144-8

Oláh, Gabor; Módis, Katalin; Gero, Domokos et al. (2011) Cytoprotective effect of ?-tocopherol against tumor necrosis factor ? induced cell dysfunction in L929 cells. Int J Mol Med 28:711-20

Asmussen, Sven; Bartha, Eva; Olah, Gabor et al. (2011) The Angiotensin-converting enzyme inhibitor captopril inhibits poly(adp-ribose) polymerase activation and exerts beneficial effects in an ovine model of burn and smoke injury. Shock 36:402-9