Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM063890-01A2S1
Application #
6735307
Study Section
Physiological Chemistry Study Section (PC)
Program Officer
Rhoades, Marcus M
Project Start
2002-09-30
Project End
2007-08-31
Budget Start
2003-06-01
Budget End
2003-08-31
Support Year
1
Fiscal Year
2003
Total Cost
$10,628
Indirect Cost

  Institution

Name
Boston College
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
045896339
City
Chestnut Hill
State
MA
Country
United States
Zip Code
02467

  Publications

Lue, Stanley W; Kelley, Shana O (2007) A single residue in leucyl-tRNA synthetase affecting amino acid specificity and tRNA aminoacylation. Biochemistry 46:4466-72
Lue, Stanley W; Kelley, Shana O (2005) An aminoacyl-tRNA synthetase with a defunct editing site. Biochemistry 44:3010-6
Zagryadskaya, Ekaterina I; Kelley, Shana O (2005) Combinatorial analysis of loop nucleotides in human mitochondrial tRNALeu(UUR). Biochemistry 44:233-42
Roy, Marc D; Wittenhagen, Lisa M; Vozzella, Brian E et al. (2004) Interdomain communication between weak structural elements within a disease-related human tRNA. Biochemistry 43:384-92
Wittenhagen, Lisa M; Roy, Marc D; Kelley, Shana O (2003) The pathogenic U3271C human mitochondrial tRNA(Leu(UUR)) mutation disrupts a fragile anticodon stem. Nucleic Acids Res 31:596-601
Wittenhagen, Lisa M; Kelley, Shana O (2003) Impact of disease-related mitochondrial mutations on tRNA structure and function. Trends Biochem Sci 28:605-11