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Borjigin, Mandula; Arenaz, Pablo; Stec, Boguslaw (2012) Chinese hamster AP endonuclease operates by a two-metal ion assisted catalytic mechanism. FEBS Lett 586:242-7
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Tolonen, Ellen; Bueno, Brenda; Kulshreshta, Sanjeev et al. (2011) Allosteric transition and binding of small molecule effectors causes curvature change in central ?-sheets of selected enzymes. J Mol Model 17:899-911
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Neelon, Kelly; Roberts, Mary F; Stec, Boguslaw (2011) Crystal structure of a trapped catalytic intermediate suggests that forced atomic proximity drives the catalysis of mIPS. Biophys J 101:2816-24
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Zhang, Ying; Stec, Boguslaw; Godzik, Adam (2007) Between order and disorder in protein structures: analysis of ""dual personality"" fragments in proteins. Structure 15:1141-7
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Rodionov, Dmitry A; Kurnasov, Oleg V; Stec, Boguslaw et al. (2007) Genomic identification and in vitro reconstitution of a complete biosynthetic pathway for the osmolyte di-myo-inositol-phosphate. Proc Natl Acad Sci U S A 104:4279-84
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Wang, Yanling; Stieglitz, Kimberly A; Bubunenko, Mikhail et al. (2007) The structure of the R184A mutant of the inositol monophosphatase encoded by suhB and implications for its functional interactions in Escherichia coli. J Biol Chem 282:26989-96
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Stec, Boguslaw; Holtz, Kathleen M; Wojciechowski, Cheryl L et al. (2005) Structure of the wild-type TEM-1 beta-lactamase at 1.55 A and the mutant enzyme Ser70Ala at 2.1 A suggest the mode of noncovalent catalysis for the mutant enzyme. Acta Crystallogr D Biol Crystallogr 61:1072-9
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Stieglitz, Kimberly A; Yang, Hongying; Roberts, Mary F et al. (2005) Reaching for mechanistic consensus across life kingdoms: structure and insights into catalysis of the myo-inositol-1-phosphate synthase (mIPS) from Archaeoglobus fulgidus. Biochemistry 44:213-24
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Neelon, Kelly; Wang, Yan; Stec, Boguslaw et al. (2005) Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase. J Biol Chem 280:11475-82
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Stieglitz, Kimberly A; Seaton, Barbara A; Head, James F et al. (2003) Unexpected similarity in regulation between an archaeal inositol monophosphatase/fructose bisphosphatase and chloroplast fructose bisphosphatase. Protein Sci 12:760-7
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