Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM065465-02
Application #
6694045
Study Section
Molecular, Cellular and Developmental Neurosciences 2 (MDCN)
Program Officer
Lograsso, Philip
Project Start
2003-01-01
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$266,640
Indirect Cost

  Institution

Name
University of Arizona
Department
Pharmacology
Type
Schools of Medicine
DUNS #
806345617
City
Tucson
State
AZ
Country
United States
Zip Code
85721

  Publications

Tumati, S; Roeske, W R; Largent-Milnes, T M et al. (2011) Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats. J Neurosci Methods 199:62-8
Tumati, Suneeta; Roeske, William R; Vanderah, Todd W et al. (2010) Sustained morphine treatment augments prostaglandin E2-evoked calcitonin gene-related peptide release from primary sensory neurons in a PKA-dependent manner. Eur J Pharmacol 648:95-101
Tumati, S; Roeske, W R; Largent-Milnes, T et al. (2010) Sustained morphine-mediated pain sensitization and antinociceptive tolerance are blocked by intrathecal treatment with Raf-1-selective siRNA. Br J Pharmacol 161:51-64
Tumati, Suneeta; Yamamura, Henry I; St John, Paul A et al. (2009) Sustained cannabinoid agonist treatment augments CGRP release in a PKA-dependent manner. Neuroreport 20:815-9
Tumati, Suneeta; Yamamura, Henry I; Vanderah, Todd W et al. (2009) Sustained morphine treatment augments capsaicin-evoked calcitonin gene-related peptide release from primary sensory neurons in a protein kinase A- and Raf-1-dependent manner. J Pharmacol Exp Ther 330:810-7
Tumati, Suneeta; Milnes, Tally Largent; Yamamura, Henry I et al. (2008) Intrathecal Raf-1-selective siRNA attenuates sustained morphine-mediated thermal hyperalgesia. Eur J Pharmacol 601:207-8