Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
5R01GM067928-07
Application #
6641081
Study Section
Metallobiochemistry Study Section (BMT)
Program Officer
Preusch, Peter C
Project Start
2002-08-01
Project End
2006-07-31
Budget Start
2003-08-01
Budget End
2004-07-31
Support Year
7
Fiscal Year
2003
Total Cost
$156,060
Indirect Cost

  Institution

Name
Miami University Oxford
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
041065129
City
Oxford
State
OH
Country
United States
Zip Code
45056

  Publications

Hu, Zhenxin; Periyannan, Gopal R; Crowder, Michael W (2008) Folding strategy to prepare Co(II)-substituted metallo-beta-lactamase L1. Anal Biochem 378:177-83
Crisp, Jonathan; Conners, Rebecca; Garrity, James D et al. (2007) Structural basis for the role of Asp-120 in metallo-beta-lactamases. Biochemistry 46:10664-74
Sharma, Narayan P; Hajdin, Christine; Chandrasekar, Sowmya et al. (2006) Mechanistic studies on the mononuclear ZnII-containing metallo-beta-lactamase ImiS from Aeromonas sobria. Biochemistry 45:10729-38
Matthews, Megan L; Periyannan, Gopalraj; Hajdin, Christine et al. (2006) Probing the reaction mechanism of the D-ala-D-ala dipeptidase, VanX, by using stopped-flow kinetic and rapid-freeze quench EPR studies on the Co(II)-substituted enzyme. J Am Chem Soc 128:13050-1
Yang, Ke-Wu; Golich, Frank C; Sigdel, Tara K et al. (2005) Phosphinate, sulfonate, and sulfonamidate dipeptides as potential inhibitors of Escherichia coli aminopeptidase N. Bioorg Med Chem Lett 15:5150-3
Marasinghe, Gishanthi P K; Sander, Ian M; Bennett, Brian et al. (2005) Structural studies on a mitochondrial glyoxalase II. J Biol Chem 280:40668-75