Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM068077-01S1
Application #
6844574
Study Section
Physiological Chemistry Study Section (PC)
Program Officer
Rhoades, Marcus M
Project Start
2003-08-01
Project End
2008-07-31
Budget Start
2003-08-01
Budget End
2004-07-31
Support Year
1
Fiscal Year
2004
Total Cost
$30,091
Indirect Cost

  Institution

Name
University of Medicine & Dentistry of NJ
Department
Genetics
Type
Schools of Medicine
DUNS #
617022384
City
Piscataway
State
NJ
Country
United States
Zip Code
08854

  Publications

Donovan, Jesse; Copeland, Paul R (2010) Threading the needle: getting selenocysteine into proteins. Antioxid Redox Signal 12:881-92
Donovan, Jesse; Caban, Kelvin; Ranaweera, Ruchira et al. (2008) A novel protein domain induces high affinity selenocysteine insertion sequence binding and elongation factor recruitment. J Biol Chem 283:35129-39
Gupta, Malavika; Copeland, Paul R (2007) Functional analysis of the interplay between translation termination, selenocysteine codon context, and selenocysteine insertion sequence-binding protein 2. J Biol Chem 282:36797-807
Caban, Kelvin; Kinzy, Scott A; Copeland, Paul R (2007) The L7Ae RNA binding motif is a multifunctional domain required for the ribosome-dependent Sec incorporation activity of Sec insertion sequence binding protein 2. Mol Cell Biol 27:6350-60
Kinzy, Scott A; Caban, Kelvin; Copeland, Paul R (2005) Characterization of the SECIS binding protein 2 complex required for the co-translational insertion of selenocysteine in mammals. Nucleic Acids Res 33:5172-80
Mehta, Anupama; Rebsch, Cheryl M; Kinzy, Scott A et al. (2004) Efficiency of mammalian selenocysteine incorporation. J Biol Chem 279:37852-9
Copeland, Paul R (2003) Regulation of gene expression by stop codon recoding: selenocysteine. Gene 312:17-25