Dynamic integration of intracellular signaling and actomyosin contractility in the early C. elegans embryo

Agency: National Institute of Health (NIH)
Institute: National Institute of General Medical Sciences (NIGMS)
Type: Research Project (R01)
Project #: 3R01GM098441-09S1
Application #: 10154399
Study Section: Nuclear and Cytoplasmic Structure/Function and Dynamics Study Section (NCSD)
Program Officer: Gindhart, Joseph G


NIH 2020 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago
NIH 2020 R01 GM	Dynamic integration of intracellular signaling and actomyosin contractility in the early C. elegans embryo Munro, Edwin Marshall / University of Chicago
NIH 2019 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago
NIH 2018 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago
NIH 2017 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago
NIH 2015 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago	$292,314
NIH 2014 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago
NIH 2013 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago	$282,083
NIH 2012 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago	$292,314
NIH 2011 R01 GM	Dynamics and regulation of actomyosin contractility in the C. elegans embryo Munro, Edwin Marshall / University of Chicago	$292,314

Wu, Youjun; Han, Bingjie; Li, Younan et al. (2018) Rapid diffusion-state switching underlies stable cytoplasmic gradients in the Caenorhabditis elegans zygote. Proc Natl Acad Sci U S A 115:E8440-E8449

McFadden, William M; McCall, Patrick M; Gardel, Margaret L et al. (2017) Filament turnover tunes both force generation and dissipation to control long-range flows in a model actomyosin cortex. PLoS Comput Biol 13:e1005811

Stam, Samantha; Alberts, Jon; Gardel, Margaret L et al. (2015) Isoforms Confer Characteristic Force Generation and Mechanosensation by Myosin II Filaments. Biophys J 108:1997-2006

Sailer, Anne; Anneken, Alexander; Li, Younan et al. (2015) Dynamic Opposition of Clustered Proteins Stabilizes Cortical Polarity in the C. elegans Zygote. Dev Cell 35:131-42

Kim, Taeyoon; Gardel, Margaret L; Munro, Ed (2014) Determinants of fluidlike behavior and effective viscosity in cross-linked actin networks. Biophys J 106:526-34

Robin, François B; McFadden, William M; Yao, Baixue et al. (2014) Single-molecule analysis of cell surface dynamics in Caenorhabditis elegans embryos. Nat Methods 11:677-82