Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Project (R01)
Project #
3R01GM123159-03S1
Application #
10134941
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Flicker, Paula F
Project Start
2018-01-01
Project End
2021-12-31
Budget Start
2020-01-01
Budget End
2020-12-31
Support Year
3
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94118

  Publications

Keedy, Daniel A; Hill, Zachary B; Biel, Justin T et al. (2018) An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife 7:
Budday, Dominik; Leyendecker, Sigrid; van den Bedem, Henry (2018) Kinematic Flexibility Analysis: Hydrogen Bonding Patterns Impart a Spatial Hierarchy of Protein Motion. J Chem Inf Model 58:2108-2122
Otten, Renee; Liu, Lin; Kenner, Lillian R et al. (2018) Rescue of conformational dynamics in enzyme catalysis by directed evolution. Nat Commun 9:1314
Wall, Michael E; Wolff, Alexander M; Fraser, James S (2018) Bringing diffuse X-ray scattering into focus. Curr Opin Struct Biol 50:109-116