Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD011827-15
Application #
2196845
Study Section
Reproductive Biology Study Section (REB)
Project Start
1978-04-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1997-12-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Shang, W; Konidari, I; Schomberg, D W (2001) 2-Methoxyestradiol, an endogenous estradiol metabolite, differentially inhibits granulosa and endothelial cell mitosis: a potential follicular antiangiogenic regulator. Biol Reprod 65:622-7
Chun, S Y; McGee, E A; Hsu, S Y et al. (1999) Restricted expression of WT1 messenger ribonucleic acid in immature ovarian follicles: uniformity in mammalian and avian species and maintenance during reproductive senescence. Biol Reprod 60:365-73
Schomberg, D W; Couse, J F; Mukherjee, A et al. (1999) Targeted disruption of the estrogen receptor-alpha gene in female mice: characterization of ovarian responses and phenotype in the adult. Endocrinology 140:2733-44
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Mulheron, G W; Bossert, N L; Lapp, J A et al. (1992) Human granulosa-luteal and cumulus cells express transforming growth factors-beta type 1 and type 2 mRNA. J Clin Endocrinol Metab 74:458-60
Mulheron, G W; Mulheron, J G; Danielpour, D et al. (1992) Porcine granulosa cells do not express transforming growth factor-beta 2 (TGF-beta 2) messenger ribonucleic acid: molecular basis for their inability to produce TGF-beta activity comparable to that of rat granulosa cells. Endocrinology 131:2609-14
Tilly, J L; Kowalski, K I; Schomberg, D W et al. (1992) Apoptosis in atretic ovarian follicles is associated with selective decreases in messenger ribonucleic acid transcripts for gonadotropin receptors and cytochrome P450 aromatase. Endocrinology 131:1670-6
Mulheron, G W; Schomberg, D W (1992) Effects of diethylstilbestrol on rat granulosa cell and thecal/interstitial cell transforming growth factor-beta 2 mRNA expression in vivo: analysis by reverse transcription-polymerase chain reaction. Biol Reprod 46:546-50
Mulheron, G W; Danielpour, D; Schomberg, D W (1991) Rat thecal/interstitial cells express transforming growth factor-beta type 1 and 2, but only type 2 is regulated by gonadotropin in vitro. Endocrinology 129:368-74
Mulheron, G W; Schomberg, D W (1990) Rat granulosa cells express transforming growth factor-beta type 2 messenger ribonucleic acid which is regulatable by follicle-stimulating hormone in vitro. Endocrinology 126:1777-9

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