Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD013425-10
Application #
3312199
Study Section
Reproductive Endocrinology Study Section (REN)
Project Start
1979-07-01
Project End
1992-03-31
Budget Start
1990-07-01
Budget End
1992-03-31
Support Year
10
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Saint Louis University
Department
Type
Schools of Medicine
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63103
Ruh, M F; Dunn 2nd, R; Ruh, T S (1996) Interrelationships between nuclear structure and ligand-activated intracellular receptors. Crit Rev Eukaryot Gene Expr 6:271-83
Ruh, M F; Cox, L K; Ruh, T S (1996) Estrogen receptor interaction with specific histones. Binding to genomic DNA and an estrogen response element. Biochem Pharmacol 52:869-78
Dunn 2nd, R T; Ruh, T S; Burroughs, L K et al. (1996) Purification and characterization of an Ah receptor binding factor in chromatin. Biochem Pharmacol 51:437-45
Dunn 2nd, R T; Ruh, T S; Ruh, M F (1993) Binding of the Ah receptor to receptor binding factors in chromatin. Biochem Pharmacol 45:1121-8
Turner, J W; Ruh, M F; Ward, D T et al. (1991) Effects of antiestrogen versus antiprogestin on transformed and nontransformed steroid receptors. J Steroid Biochem Mol Biol 38:197-203
Ruh, M F; Turner, J W; Paulson, C M et al. (1990) Differences in the form of the salt-transformed estrogen receptor when bound by estrogen versus antiestrogen. J Steroid Biochem 36:509-16
Singh, R K; Ruh, M F; Butler, W B et al. (1986) Acceptor sites on chromatin for receptor bound by estrogen versus antiestrogen in antiestrogen-sensitive and -resistant MCF-7 cells. Endocrinology 118:1087-95
Ruh, M F; Singh, R K; Mak, P et al. (1986) Tissue and species specificity of unmasked nuclear acceptor sites for the estrogen receptor of Squalus testes. Endocrinology 118:811-8
Shyamala, G; Singh, R K; Ruh, M F et al. (1986) Relationships between mammary estrogen receptor and estrogenic sensitivity. II. Binding of cytoplasmic receptor to chromatin. Endocrinology 119:819-26
Sheen, Y Y; Ruh, T S; Mangel, W F et al. (1985) Antiestrogenic potency and binding characteristics of the triphenylethylene H1285 in MCF-7 human breast cancer cells. Cancer Res 45:4192-9

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