Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD014405-07
Application #
3312573
Study Section
Human Embryology and Development Subcommittee 2 (HED)
Project Start
1980-08-01
Project End
1987-09-28
Budget Start
1987-04-01
Budget End
1987-09-28
Support Year
7
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Upstate Medical University
Department
Type
Schools of Medicine
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210
Kuhn, D C; Walenga, R W; Stuart, M J (1991) A prostacyclin analogue crosses the in vitro perfused human placenta and improves transfer in some pathologic states. Am J Perinatol 8:179-84
Kuhn, D C; Crawford, M A; Stuart, M J et al. (1990) Alterations in transfer and lipid distribution of arachidonic acid in placentas of diabetic pregnancies. Diabetes 39:914-8
Walenga, R W; Kuhn, D C; Stuart, M J (1989) Trans-placental transport and metabolism of carbacyclin by perfused human placental in vitro. Prostaglandins 37:121-34
Walenga, R W; Sunderji, S; Stuart, M J (1988) Formation of hydroxyeicosatetraenoic acids (HETE) in blood from adults versus neonates: reduced production of 12-HETE in cord blood. Pediatr Res 24:563-7
Kuhn, D C; Crawford, M A; Gordon, G B et al. (1988) Aspects of in vitro placental perfusion: effects of hyperoxia and phenol red. Placenta 9:201-13
Walenga, R W; Boone, S; Stuart, M J (1987) Analysis of blood HETE levels by selected ion monitoring with ricinoleic acid as the internal standard. Prostaglandins 34:733-48
Sadowitz, P D; Setty, B N; Stuart, M (1987) The platelet cyclooxygenase metabolite 12-L-hydroxy-5, 8, 10-hepta-decatrienoic acid (HHT) may modulate primary hemostasis by stimulating prostacyclin production. Prostaglandins 34:749-63
Setty, B N; Dubowy, R L; Stuart, M J (1987) Endothelial cell proliferation may be mediated via the production of endogenous lipoxygenase metabolites. Biochem Biophys Res Commun 144:345-51
Kuhn, D C; Stuart, M J (1987) Cyclooxygenase inhibition reduces placental transfer: reversal by carbacyclin. Am J Obstet Gynecol 157:194-8
Setty, B N; Berger, M; Stuart, M J (1987) 13-Hydroxyoctadecadienoic acid (13-HODE) stimulates prostacyclin production by endothelial cells. Biochem Biophys Res Commun 146:502-9

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