Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD016149-11
Application #
2197272
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1982-09-30
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1998-04-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Population Council
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10017
Kanzaki, M; Morris, P L (1999) Growth hormone regulates steroidogenic acute regulatory protein expression and steroidogenesis in Leydig cell progenitors. Endocrinology 140:1681-6
Kanzaki, M; Morris, P L (1998) Lactogenic hormone-inducible phosphorylation and gamma-activated site-binding activities of Stat5b in primary rat Leydig cells and MA-10 mouse Leydig tumor cells. Endocrinology 139:1872-82
Jenab, S; Morris, P L (1998) Testicular leukemia inhibitory factor (LIF) and LIF receptor mediate phosphorylation of signal transducers and activators of transcription (STAT)-3 and STAT-1 and induce c-fos transcription and activator protein-1 activation in rat Sertoli but not germ ce Endocrinology 139:1883-90
Kanzaki, M; Morris, P L (1998) Identification and regulation of testicular interferon-gamma (IFNgamma) receptor subunits: IFNgamma enhances interferon regulatory factor-1 and interleukin-1beta converting enzyme expression. Endocrinology 139:2636-44
Jenab, S; Morris, P L (1997) Transcriptional regulation of Sertoli cell immediate early genes by interleukin-6 and interferon-gamma is mediated through phosphorylation of STAT-3 and STAT-1 proteins. Endocrinology 138:2740-6
Jenab, S; Morris, P L (1996) Differential activation of signal transducer and activator of transcription (STAT)-3 and STAT-1 transcription factors and c-fos messenger ribonucleic acid by interleukin-6 and interferon-gamma in Sertoli cells. Endocrinology 137:4738-43
Boffa, L C; Morris, P L; Carpaneto, E M et al. (1996) Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence. J Biol Chem 271:13228-33
Okuda, Y; Bardin, C W; Hodgskin, L R et al. (1995) Interleukins-1 alpha and -1 beta regulate interleukin-6 expression in Leydig and Sertoli cells. Recent Prog Horm Res 50:367-72
Morris, P L; Hodgskin, L R; Fujisawa, M (1994) A spermatid factor inhibits cAMP and calcium signaling in Sertoli but not Leydig cells. Recent Prog Horm Res 49:353-8
Fantoni, G; Morris, P L; Forti, G et al. (1993) Endothelin-1: a new autocrine/paracrine factor in rat testis. Am J Physiol 265:E267-74

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