Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
2R01HD016659-14
Application #
2197341
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1982-09-01
Project End
2000-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Hansen, R Scott; Thomas, Sean; Sandstrom, Richard et al. (2010) Sequencing newly replicated DNA reveals widespread plasticity in human replication timing. Proc Natl Acad Sci U S A 107:139-44
De Bonis, M L; Cerase, A; Matarazzo, M R et al. (2006) Maintenance of X- and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications. Hum Mol Genet 15:1123-32
Gartler, Stanley M; Varadarajan, Kartik R; Luo, Ping et al. (2006) Abnormal X: autosome ratio, but normal X chromosome inactivation in human triploid cultures. BMC Genet 7:41
Burden, Alice F; Manley, Nathan C; Clark, Aaron D et al. (2005) Hemimethylation and non-CpG methylation levels in a promoter region of human LINE-1 (L1) repeated elements. J Biol Chem 280:14413-9
Miner, Brooks E; Stoger, Reinhard J; Burden, Alice F et al. (2004) Molecular barcodes detect redundancy and contamination in hairpin-bisulfite PCR. Nucleic Acids Res 32:e135
Laird, Charles D; Pleasant, Nicole D; Clark, Aaron D et al. (2004) Hairpin-bisulfite PCR: assessing epigenetic methylation patterns on complementary strands of individual DNA molecules. Proc Natl Acad Sci U S A 101:204-9
Gartler, Stanley M; Varadarajan, Kartik R; Luo, Ping et al. (2004) Normal histone modifications on the inactive X chromosome in ICF and Rett syndrome cells: implications for methyl-CpG binding proteins. BMC Biol 2:21
Hansen, R Scott (2003) X inactivation-specific methylation of LINE-1 elements by DNMT3B: implications for the Lyon repeat hypothesis. Hum Mol Genet 12:2559-67
Gartler, S M; Hansen, R S (2002) ICF syndrome cells as a model system for studying X chromosome inactivation. Cytogenet Genome Res 99:25-9
Matarazzo, Maria Rosaria; De Bonis, Maria Luigia; Gregory, Richard I et al. (2002) Allelic inactivation of the pseudoautosomal gene SYBL1 is controlled by epigenetic mechanisms common to the X and Y chromosomes. Hum Mol Genet 11:3191-8

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