Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
3R01HD018983-03S1
Application #
3316127
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1984-12-01
Project End
1988-06-30
Budget Start
1987-12-01
Budget End
1988-06-30
Support Year
3
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Kretz, K A; O'Brien, J S (1993) Direct sequencing of polymerase chain reaction products from low melting temperature agarose. Methods Enzymol 218:72-9
Tayama, M; Soeda, S; Kishimoto, Y et al. (1993) Effect of saposins on acid sphingomyelinase. Biochem J 290 ( Pt 2):401-4
Tayama, M; O'Brien, J S; Kishimoto, Y (1992) Distribution of saposins (sphingolipid activator proteins) in tissues of lysosomal storage disease patients. J Mol Neurosci 3:171-5
Kretz, K A; Cripe, D; Carson, G S et al. (1992) Structure and sequence of the human alpha-L-fucosidase gene and pseudogene. Genomics 12:276-80
Kishimoto, Y; Hiraiwa, M; O'Brien, J S (1992) Saposins: structure, function, distribution, and molecular genetics. J Lipid Res 33:1255-67
O'Brien, J S; Kishimoto, Y (1991) Saposin proteins: structure, function, and role in human lysosomal storage disorders. FASEB J 5:301-8
Hiraiwa, M; Uda, Y; Tsuji, S et al. (1991) Human placental sialidase complex: characterization of the 60 kDa protein that cross-reacts with anti-saposin antibodies. Biochem Biophys Res Commun 177:1211-6
Morimoto, S; Yamamoto, Y; O'Brien, J S et al. (1990) Distribution of saposin proteins (sphingolipid activator proteins) in lysosomal storage and other diseases. Proc Natl Acad Sci U S A 87:3493-7
Morimoto, S; Kishimoto, Y; Tomich, J et al. (1990) Interaction of saposins, acidic lipids, and glucosylceramidase. J Biol Chem 265:1933-7
Kretz, K A; Carson, G S; Morimoto, S et al. (1990) Characterization of a mutation in a family with saposin B deficiency: a glycosylation site defect. Proc Natl Acad Sci U S A 87:2541-4

Showing the most recent 10 out of 27 publications