Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD020583-05
Application #
3318825
Study Section
Biochemical Endocrinology Study Section (BCE)
Project Start
1986-12-01
Project End
1991-08-31
Budget Start
1990-12-01
Budget End
1991-08-31
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Levine, E; Cupp, A S; Miyashiro, L et al. (2000) Role of transforming growth factor-alpha and the epidermal growth factor receptor in embryonic rat testis development. Biol Reprod 62:477-90
Chaudhary, J; Cupp, A S; Skinner, M K (1997) Role of basic-helix-loop-helix transcription factors in Sertoli cell differentiation: identification of an E-box response element in the transferrin promoter. Endocrinology 138:667-75
Chaudhary, J; Whaley, P D; Cupp, A et al. (1996) Transcriptional regulation of sertoli cell differentiation by follicle-stimulating hormone at the level of the c-fos and transferrin promoters. Biol Reprod 54:692-9
Chaudhary, J; Skinner, M K (1995) Transcriptional regulation of Sertoli cell differentiation (transferrin promoter activation) during testicular development. Dev Genet 16:114-8
Whaley, P D; Chaudhary, J; Cupp, A et al. (1995) Role of specific response elements of the c-fos promoter and involvement of intermediate transcription factor(s) in the induction of Sertoli cell differentiation (transferrin promoter activation) by the testicular paracrine factor PModS. Endocrinology 136:3046-53
Mullaney, B P; Rosselli, M; Skinner, M K (1994) Developmental regulation of Sertoli cell lactate production by hormones and the testicular paracrine factor, PModS. Mol Cell Endocrinol 104:67-73
Norton, J N; Vigne, J L; Skinner, M K (1994) Regulation of Sertoli cell differentiation by the testicular paracrine factor PModS: analysis of common signal transduction pathways. Endocrinology 134:149-57
Mullaney, B P; Skinner, M K (1993) Transforming growth factor-beta (beta 1, beta 2, and beta 3) gene expression and action during pubertal development of the seminiferous tubule: potential role at the onset of spermatogenesis. Mol Endocrinol 7:67-76
Norton, J N; Skinner, M K (1992) Regulation of Sertoli cell differentiation by the testicular paracrine factor PModS: potential role of immediate-early genes. Mol Endocrinol 6:2018-26
Risbridger, G P; Skinner, M K (1992) Evaluation of the effect of peritubular cell secretions and the testicular paracrine factor P-Mod-S on Leydig cell steroidogenesis and immunoactive inhibin production. Int J Androl 15:73-83

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