Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD022416-08
Application #
2198527
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1989-02-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1997-03-31
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Southern California
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Kundu, R K; Sangiorgi, F; Wu, L Y et al. (1999) Expression of the human immunodeficiency virus-Tat gene in lymphoid tissues of transgenic mice is associated with B-cell lymphoma. Blood 94:275-82
Tan, H; Ransick, A; Wu, H et al. (1998) Disruption of primary mesenchyme cell patterning by misregulated ectodermal expression of SpMsx in sea urchin embryos. Dev Biol 201:230-46
Kundu, R K; Sangiorgi, F; Wu, L Y et al. (1998) Targeted inactivation of the coagulation factor IX gene causes hemophilia B in mice. Blood 92:168-74
Wu, L; Wu, H; Ma, L et al. (1997) Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA. Mech Dev 65:3-17
Ma, L; Swalla, B J; Zhou, J et al. (1996) Expression of an Msx homeobox gene in ascidians: insights into the archetypal chordate expression pattern. Dev Dyn 205:308-18
Ma, L; Golden, S; Wu, L et al. (1996) The molecular basis of Boston-type craniosynostosis: the Pro148-->His mutation in the N-terminal arm of the MSX2 homeodomain stabilizes DNA binding without altering nucleotide sequence preferences. Hum Mol Genet 5:1915-20
Lazik, A; Liu, Y; Bringas, P et al. (1996) A sensitive method for analyzing beta-galactosidase reporter gene expression in tissue sections of mouse embryos. Trends Genet 12:445-7
Liu, Y H; Ma, L; Kundu, R et al. (1996) Function of the Msx2 gene in the morphogenesis of the skull. Ann N Y Acad Sci 785:48-58
Liu, Y H; Kundu, R; Wu, L et al. (1995) Premature suture closure and ectopic cranial bone in mice expressing Msx2 transgenes in the developing skull. Proc Natl Acad Sci U S A 92:6137-41
Liu, Y H; Ma, L; Wu, L Y et al. (1994) Regulation of the Msx2 homeobox gene during mouse embryogenesis: a transgene with 439 bp of 5' flanking sequence is expressed exclusively in the apical ectodermal ridge of the developing limb. Mech Dev 48:187-97

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