Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD024191-03
Application #
3324655
Study Section
Reproductive Biology Study Section (REB)
Project Start
1988-07-01
Project End
1992-03-31
Budget Start
1990-07-01
Budget End
1992-03-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02111
Ducibella, Tom; Fissore, Rafael (2008) The roles of Ca2+, downstream protein kinases, and oscillatory signaling in regulating fertilization and the activation of development. Dev Biol 315:257-79
Ducibella, Tom; Schultz, Richard M; Ozil, Jean-Pierre (2006) Role of calcium signals in early development. Semin Cell Dev Biol 17:324-32
Matson, Sara; Markoulaki, Styliani; Ducibella, Tom (2006) Antagonists of myosin light chain kinase and of myosin II inhibit specific events of egg activation in fertilized mouse eggs. Biol Reprod 74:169-76
Ozil, Jean-Pierre; Markoulaki, Styliani; Toth, Szabolcs et al. (2005) Egg activation events are regulated by the duration of a sustained [Ca2+]cyt signal in the mouse. Dev Biol 282:39-54
Abbott, A L; Ducibella, T (2001) Calcium and the control of mammalian cortical granule exocytosis. Front Biosci 6:D792-806
Abbott, A L; Fissore, R A; Ducibella, T (2001) Identification of a translocation deficiency in cortical granule secretion in preovulatory mouse oocytes. Biol Reprod 65:1640-7
Gross, V S; Wessel, G; Florman, H M et al. (2000) A monoclonal antibody that recognizes mammalian cortical granules and a 32-kilodalton protein in mouse eggs. Biol Reprod 63:575-81
Abbott, A L; Fissore, R A; Ducibella, T (1999) Incompetence of preovulatory mouse oocytes to undergo cortical granule exocytosis following induced calcium oscillations. Dev Biol 207:38-48
Ducibella, T (1998) Biochemical and cellular insights into the temporal window of normal fertilization. Theriogenology 49:53-65
Abbott, A L; Xu, Z; Kopf, G S et al. (1998) In vitro culture retards spontaneous activation of cell cycle progression and cortical granule exocytosis that normally occur in in vivo unfertilized mouse eggs. Biol Reprod 59:1515-21

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