Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD026171-07
Application #
2199855
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1989-09-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Shirai, Yasuhito; Balsinde, Jesus; Dennis, Edward A (2005) Localization and functional interrelationships among cytosolic Group IV, secreted Group V, and Ca2+-independent Group VI phospholipase A2s in P388D1 macrophages using GFP/RFP constructs. Biochim Biophys Acta 1735:119-29
Balboa, Maria A; Shirai, Yasuhito; Gaietta, Guido et al. (2003) Localization of group V phospholipase A2 in caveolin-enriched granules in activated P388D1 macrophage-like cells. J Biol Chem 278:48059-65
Balboa, Maria A; Varela-Nieto, Isabel; Killermann Lucas, Karin et al. (2002) Expression and function of phospholipase A(2) in brain. FEBS Lett 531:12-7
Bernatchez, P N; Winstead, M V; Dennis, E A et al. (2001) VEGF stimulation of endothelial cell PAF synthesis is mediated by group V 14 kDa secretory phospholipase A2. Br J Pharmacol 134:197-205
Balboa, M A; Balsinde, J; Dennis, E A (2001) Inflammatory activation of prostaglandin production by microglial cells antagonized by amyloid peptide. Biochem Biophys Res Commun 280:558-60
Winstead, M V; Balsinde, J; Dennis, E A (2000) Calcium-independent phospholipase A(2): structure and function. Biochim Biophys Acta 1488:28-39
Balsinde, J; Balboa, M A; Dennis, E A (2000) Group IV cytosolic phospholipase A2 activation by diacylglycerol pyrophosphate in murine P388D1 macrophages. Ann N Y Acad Sci 905:5-Nov
Deems, R A (2000) Interfacial enzyme kinetics at the phospholipid/water interface: practical considerations. Anal Biochem 287:16-Jan
Balboa, M A; Balsinde, J; Dennis, E A (2000) Phosphorylation of cytosolic group IV phospholipase A(2) is necessary but not sufficient for Arachidonic acid release in P388D(1) macrophages. Biochem Biophys Res Commun 267:145-8
Balsinde, J; Balboa, M A; Dennis, E A (2000) Identification of a third pathway for arachidonic acid mobilization and prostaglandin production in activated P388D1 macrophage-like cells. J Biol Chem 275:22544-9

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