Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
3R01HD027444-03S1
Application #
3329111
Study Section
Special Emphasis Panel (SRC (10))
Project Start
1991-02-10
Project End
1996-01-31
Budget Start
1993-04-01
Budget End
1994-01-31
Support Year
3
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Wayne State University
Department
Type
Schools of Medicine
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Zachar, V; Zacharova, V; Fink, T et al. (1999) Genetic analysis reveals ongoing HIV type 1 evolution in infected human placental trophoblast. AIDS Res Hum Retroviruses 15:1673-83
Chi, K D; McPhee, R A; Wagner, A S et al. (1997) Integration of proviral DNA into the PDGF beta-receptor gene in HTLV-I-infected T-cells results in a novel tyrosine kinase product with transforming activity. Oncogene 15:1051-7
Zacharova, V; Becker, M L; Zachar, V et al. (1997) DNA sequence analysis of the long terminal repeat of the C subtype of human immunodeficiency virus type 1 from Southern Africa reveals a dichotomy between B subtype and African subtypes on the basis of upstream NF-IL6 motif. AIDS Res Hum Retroviruses 13:719-24
Zachar, V; Hager, H; Koppelhus, U et al. (1997) Elevated interferon-alpha in maternal and umbilical cord blood and in the placental trophoblast suggests natural protection against vertical transmission of HIV-1 in a Kenyan cohort. AIDS 11:383-5
Zacharova, V; Zachar, V; Goustin, A S (1997) Sequence of chemokine receptor gene CCR5 in chimpanzees, a natural HIV type 1 host. AIDS Res Hum Retroviruses 13:1159-61
Zachar, V; Mayer, V; Zacharova, V et al. (1996) Spread of HIV type 1 in Slovakia remains limited and is restricted to subtype B. AIDS Res Hum Retroviruses 12:1069-71
Zachar, V; Goustin, A S; Zacharova, V et al. (1996) Genetic polymorphism of envelope V3 region of HIV type 1 subtypes A, C, and D from Nairobi, Kenya. AIDS Res Hum Retroviruses 12:75-8
Zachar, V; Ebbesen, P; Thomas, R A et al. (1994) Basal and Tat-transactivated expression from the human immunodeficiency virus type 1 long terminal repeat in human placental trophoblast rules out promoter-enhancer activation as the partial block to viral replication. J Gen Virol 75 ( Pt 6):1461-8
Zachar, V; Thomas, R A; Goustin, A S (1993) Absolute quantification of target DNA: a simple competitive PCR for efficient analysis of multiple samples. Nucleic Acids Res 21:2017-8