Cognitive Development in Children: Genetic Markers

Plomin, Robert

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
• Type: Research Project (R01)
• Project #: 5R01HD027694-08
• Application #: 6520877
• Study Section: Special Emphasis Panel (ZRG1-SNEM-2 (01))
• Program Officer: Freund, Lisa S
• Project Start: 1991-09-01
• Project End: 2004-05-31
• Budget Start: 2002-06-01
• Budget End: 2003-05-31
• Support Year: 8
• Fiscal Year: 2002
• Total Cost: $413,573

Institution

• Name: University of London Institute of Psychiatry
• City: London
• Country: United Kingdom

Publications

Krapohl, E; Euesden, J; Zabaneh, D et al. (2016) Phenome-wide analysis of genome-wide polygenic scores. Mol Psychiatry 21:1188-93

Loat, C S; Craig, G; Plomin, R et al. (2006) Investigating the relationship between FMR1 allele length and cognitive ability in children: a subtle effect of the normal allele range on the normal ability range? Ann Hum Genet 70:555-65

Galsworthy, Michael J; Paya-Cano, Jose L; Liu, Lin et al. (2005) Assessing reliability, heritability and general cognitive ability in a battery of cognitive tasks for laboratory mice. Behav Genet 35:675-92

Fernandes, Cathy; Paya-Cano, Jose L; Sluyter, Frans et al. (2004) Hippocampal gene expression profiling across eight mouse inbred strains: towards understanding the molecular basis for behaviour. Eur J Neurosci 19:2576-82

Plomin, R; Turic, D M; Hill, L et al. (2004) A functional polymorphism in the succinate-semialdehyde dehydrogenase (aldehyde dehydrogenase 5 family, member A1) gene is associated with cognitive ability. Mol Psychiatry 9:582-6

Mill, J; Galsworthy, M J; Paya-Cano, J L et al. (2002) Home-cage activity in heterogeneous stock (HS) mice as a model of baseline activity. Genes Brain Behav 1:166-73

Hill, Linzy; Chorney, Michael J; Lubinski, David et al. (2002) A quantitative trait locus not associated with cognitive ability in children: a failure to replicate. Psychol Sci 13:561-2

Turic, D; Fisher, P J; Plomin, R et al. (2001) No association between apolipoprotein E polymorphisms and general cognitive ability in children. Neurosci Lett 299:97-100

Plomin, R; Hill, L; Craig, I W et al. (2001) A genome-wide scan of 1842 DNA markers for allelic associations with general cognitive ability: a five-stage design using DNA pooling and extreme selected groups. Behav Genet 31:497-509

Plomin, R; Craig, I (2001) Genetics, environment and cognitive abilities: review and work in progress towards a genome scan for quantitative trait locus associations using DNA pooling. Br J Psychiatry Suppl 40:s41-8