Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD029264-04
Application #
2201695
Study Section
Special Emphasis Panel (SRC (10))
Project Start
1992-06-01
Project End
1998-05-31
Budget Start
1995-06-01
Budget End
1998-05-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Illinois Urbana-Champaign
Department
Nutrition
Type
Schools of Earth Sciences/Natur
DUNS #
041544081
City
Champaign
State
IL
Country
United States
Zip Code
61820
Park, Y K; Dudley, M A; Burrin, D G et al. (2001) Intestinal protein and LPH synthesis in parenterally fed piglets receiving partial enteral nutrition and enteral insulinlike growth factor 1. J Pediatr Gastroenterol Nutr 33:189-95
Houle, V M; Park, Y K; Laswell, S C et al. (2000) Investigation of three doses of oral insulin-like growth factor-I on jejunal lactase phlorizin hydrolase activity and gene expression and enterocyte proliferation and migration in piglets. Pediatr Res 48:497-503
Donovan, S M; Chao, J C; Zijlstra, R T et al. (1997) Orally administered iodinated recombinant human insulin-like growth factor-I (125I-rhIGF-I) is poorly absorbed by the newborn piglet. J Pediatr Gastroenterol Nutr 24:174-82
Houle, V M; Schroeder, E A; Odle, J et al. (1997) Small intestinal disaccharidase activity and ileal villus height are increased in piglets consuming formula containing recombinant human insulin-like growth factor-I. Pediatr Res 42:78-86
Chao, J C; Donovan, S (1996) Effects of insulin, insulin-like growth factors and epidermal growth factor on mitogenesis and disaccharidase activity in rat (IEC-6) and human (FHs 74 Int) intestinal cells. Chin J Physiol 39:253-63
Odle, J; Zijlstra, R T; Donovan, S M (1996) Intestinal effects of milkborne growth factors in neonates of agricultural importance. J Anim Sci 74:2509-22
Donovan, S M; Zijlstra, R T; Odle, J (1994) Use of the piglet to study the role of growth factors in neonatal intestinal development. Endocr Regul 28:153-62
Donovan, S M; McNeil, L K; Jimenez-Flores, R et al. (1994) Insulin-like growth factors and insulin-like growth factor binding proteins in porcine serum and milk throughout lactation. Pediatr Res 36:159-68