Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD029758-04
Application #
2202138
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1993-02-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Pharmacology
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Nakashima, S; Ohguchi, K; Frohman, M A et al. (1998) Increased mRNA expression of phospholipase D (PLD) isozymes during granulocytic differentiation of HL60 cells. Biochim Biophys Acta 1389:173-7
Liang, J O; Sung, T C; Morris, A J et al. (1997) Different domains of mammalian ADP-ribosylation factor 1 mediate interaction with selected target proteins. J Biol Chem 272:33001-8
Colley, W C; Sung, T C; Roll, R et al. (1997) Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization. Curr Biol 7:191-201
Colley, W C; Altshuller, Y M; Sue-Ling, C K et al. (1997) Cloning and expression analysis of murine phospholipase D1. Biochem J 326 ( Pt 3):745-53
Chen, Y G; Siddhanta, A; Austin, C D et al. (1997) Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network. J Cell Biol 138:495-504
Sung, T C; Roper, R L; Zhang, Y et al. (1997) Mutagenesis of phospholipase D defines a superfamily including a trans-Golgi viral protein required for poxvirus pathogenicity. EMBO J 16:4519-30
Hammond, S M; Jenco, J M; Nakashima, S et al. (1997) Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha. J Biol Chem 272:3860-8
Altshuller, Y; Copeland, N G; Gilbert, D J et al. (1996) Gcm1, a mammalian homolog of Drosophila glial cells missing. FEBS Lett 393:201-4
Frohman, M A; Morris, A J (1996) Rho is only ARF the story. Phospholipid signalling. Curr Biol 6:945-7
Hammond, S M; Altshuller, Y M; Sung, T C et al. (1995) Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family. J Biol Chem 270:29640-3

Showing the most recent 10 out of 12 publications