Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
1R01HD033016-01A1
Application #
2206361
Study Section
Epidemiology and Disease Control Subcommittee 2 (EDC)
Project Start
1996-08-10
Project End
2000-07-31
Budget Start
1996-08-10
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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Escobar, Patricia A; Olivero, Ofelia A; Wade, Nancy A et al. (2007) Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC. Environ Mol Mutagen 48:330-43
Nukui, Tomoko; Day, Richard D; Gordish-Dressman, Heather A et al. (2006) The absence of interaction between drug metabolizing enzyme genotypes and maternal lifestyle factors on glycophorin A somatic mutation frequency levels in newborns. Pharmacogenet Genomics 16:129-38
Grant, Stephen G (2005) Qualitatively and quantitatively similar effects of active and passive maternal tobacco smoke exposure on in utero mutagenesis at the HPRT locus. BMC Pediatr 5:20
Keohavong, Phouthone; Xi, Liqiang; Day, Richard D et al. (2005) HPRT gene alterations in umbilical cord blood T-lymphocytes in newborns of mothers exposed to tobacco smoke during pregnancy. Mutat Res 572:156-66
Evdokimova, Viktoria N; McLoughlin, Reagan K; Wenger, Sharon L et al. (2005) Use of the glycophorin A somatic mutation assay for rapid, unambiguous identification of Fanconi anemia homozygotes regardless of GPA genotype. Am J Med Genet A 135:59-65
Nukui, Tomoko; Day, Richard D; Sims, Cynthia S et al. (2004) Maternal/newborn GSTT1 null genotype contributes to risk of preterm, low birthweight infants. Pharmacogenetics 14:569-76
Scheerer, J B; Xi, L; Knapp, G W et al. (1999) Quantification of illegitimate V(D)J recombinase-mediated mutations in lymphocytes of newborns and adults. Mutat Res 431:291-303
Bigbee, W L; Day, R D; Grant, S G et al. (1999) Impact of maternal lifestyle factors on newborn HPRT mutant frequencies and molecular spectrum--initial results from the Prenatal Exposures and Preeclampsia Prevention (PEPP) Study. Mutat Res 431:279-89