Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD033440-02
Application #
2206917
Study Section
Special Emphasis Panel (ZRG2-HED-2 (01))
Project Start
1995-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Genetics
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Runyan, Christopher; Schaible, Kyle; Molyneaux, Kathleen et al. (2006) Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration. Development 133:4861-9
Takeuchi, Yutaka; Molyneaux, Kathleen; Runyan, Chris et al. (2005) The roles of FGF signaling in germ cell migration in the mouse. Development 132:5399-409
Stebler, Jurg; Spieler, Derek; Slanchev, Krasimir et al. (2004) Primordial germ cell migration in the chick and mouse embryo: the role of the chemokine SDF-1/CXCL12. Dev Biol 272:351-61
Molyneaux, Kathleen A; Wang, Ying; Schaible, Kyle et al. (2004) Transcriptional profiling identifies genes differentially expressed during and after migration in murine primordial germ cells. Gene Expr Patterns 4:167-81
Stallock, James; Molyneaux, Kathy; Schaible, Kyle et al. (2003) The pro-apoptotic gene Bax is required for the death of ectopic primordial germ cells during their migration in the mouse embryo. Development 130:6589-97
Molyneaux, Kathleen A; Zinszner, Helene; Kunwar, Prabhat S et al. (2003) The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival. Development 130:4279-86
Molyneaux, Kathleen A; Schaible, Kyle; Wylie, Christopher (2003) GP130, the shared receptor for the LIF/IL6 cytokine family in the mouse, is not required for early germ cell differentiation, but is required cell-autonomously in oocytes for ovulation. Development 130:4287-94
Anderson, O; Heasman, J; Wylie, C (2001) Early events in the mammalian germ line. Int Rev Cytol 203:215-30
Molyneaux, K A; Stallock, J; Schaible, K et al. (2001) Time-lapse analysis of living mouse germ cell migration. Dev Biol 240:488-98
Bendel-Stenzel, M R; Gomperts, M; Anderson, R et al. (2000) The role of cadherins during primordial germ cell migration and early gonad formation in the mouse. Mech Dev 91:143-52

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