Sterol Metabolism During Pregnancy and Development

Woollett, Laura A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
• Type: Research Project (R01)
• Project #: 7R01HD034089-02
• Application #: 2657550
• Study Section: Metabolism Study Section (MET)
• Project Start: 1997-04-01
• Project End: 2001-03-31
• Budget Start: 1997-09-01
• Budget End: 1998-03-31
• Support Year: 2
• Fiscal Year: 1997

Institution

• Name: University of Cincinnati
• Department: Pathology
• Type: Schools of Medicine
• City: Cincinnati
• State: OH
• Country: United States
• Zip Code: 45221

Publications

Rebholz, Sandra L; Jones, Thomas; Burke, Katie T et al. (2012) Multiparity leads to obesity and inflammation in mothers and obesity in male offspring. Am J Physiol Endocrinol Metab 302:E449-57

Rebholz, Sandra L; Burke, Katie T; Yang, Qing et al. (2011) Dietary fat impacts fetal growth and metabolism: uptake of chylomicron remnant core lipids by the placenta. Am J Physiol Endocrinol Metab 301:E416-25

Woollett, L A (2011) Review: Transport of maternal cholesterol to the fetal circulation. Placenta 32 Suppl 2:S218-21

Jones, Helen N; Woollett, Laura A; Barbour, Nicolette et al. (2009) High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice. FASEB J 23:271-8

Burke, Katie T; Colvin, Perry L; Myatt, Leslie et al. (2009) Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster. J Lipid Res 50:1146-55

Yao, Lihang; Horn, Paul S; Heubi, James E et al. (2007) The liver plays a key role in whole body sterol accretion of the neonatal Golden Syrian hamster. Biochim Biophys Acta 1771:550-7

Yao, Lihang; Woollett, Laura A (2005) Adult sterol metabolism is not affected by a positive sterol balance in the neonatal Golden Syrian hamster. Am J Physiol Regul Integr Comp Physiol 288:R561-6

Woollett, Laura A (2005) Maternal cholesterol in fetal development: transport of cholesterol from the maternal to the fetal circulation. Am J Clin Nutr 82:1155-61

Hayden Lichtenberg, M; Wilke, Catherine S; McConihay, Julie A et al. (2005) Yolk sac cholesteryl ester secretion rates can be manipulated in the Golden Syrian hamster: effect of yolk sac cholesterol concentrations. Biochim Biophys Acta 1735:214-21

Yao, Lihang; Dawson, Paul A; Woollett, Laura A (2003) Increases in biliary cholesterol-to-bile acid ratio in pregnant hamsters fed low and high levels of cholesterol. Am J Physiol Gastrointest Liver Physiol 284:G263-8