The proposed 4-year project will be the first to investigate the effects of measured school environments on cognitive development and academic achievement using a genetically sensitive design. The proposed research will test the hypothesis that genes play a part in mediating the effects of the school environment on educationally relevant behaviors, that is, that children actively select, modify and create environments that are correlated with their genetic propensities. It is also hypothesized that educational influences on cognitive development and academic achievement involve non-shared as well as shared environment. That is, even twins in the same classroom experience different educational environments and these nons-hared environments affect educational outcomes. The project will capitalize on a large twin study of behavioral development in childhood in which 7500 twin pairs born in 1994-96 have been assessed at 2, 3, 4 and 7 years on measures of cognition, language and behavior problems. We plan to assess each child's school and classroom environments at 10 years of age as perceived by the children themselves, as well as their parents and teachers. We will also assess cognitive development and academic achievement in order to test the hypothesis that school environments and their relationship to educational outcomes are in part mediated by genetics. The significance of finding genetic influence on educational experiences and their association with educational outcomes comes from bridging the gulf between the fields of education and genetics. Finding genetic influence will not denigrate the role of education but will suggest new ways of thinking about effective education, such as recognizing that children create their own experience within the educational process in part on the basis of their genetic propensities.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD044454-02
Application #
6995368
Study Section
Behavioral Genetics and Epidemiology Study Section (BGES)
Program Officer
Freund, Lisa S
Project Start
2004-12-15
Project End
2008-11-30
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
2
Fiscal Year
2006
Total Cost
$404,889
Indirect Cost
Name
King's College London
Department
Type
DUNS #
231876178
City
London
State
Country
United Kingdom
Zip Code
WC2 -2LS
Zabaneh, D; Krapohl, E; Gaspar, H A et al. (2018) A genome-wide association study for extremely high intelligence. Mol Psychiatry 23:1226-1232
Rimfeld, Kaili; Krapohl, Eva; Trzaskowski, Maciej et al. (2018) Genetic influence on social outcomes during and after the Soviet era in Estonia. Nat Hum Behav 2:269-275
Lewis, Gary J; Shakeshaft, Nicolas G; Plomin, Robert (2018) Face Identity Recognition and the Social Difficulties Component of the Autism-Like Phenotype: Evidence for Phenotypic and Genetic Links. J Autism Dev Disord 48:2758-2765
Selzam, S; Krapohl, E; von Stumm, S et al. (2018) Predicting educational achievement from DNA. Mol Psychiatry 23:161
PardiƱas, Antonio F; Holmans, Peter; Pocklington, Andrew J et al. (2018) Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nat Genet 50:381-389
Wang, R Adele H; Davis, Oliver S P; Wootton, Robyn E et al. (2017) Social support and mental health in late adolescence are correlated for genetic, as well as environmental, reasons. Sci Rep 7:13088
Sallis, Hannah; Evans, Jonathan; Wootton, Robyn et al. (2017) Genetics of depressive symptoms in adolescence. BMC Psychiatry 17:321
Rimfeld, Kaili; Shakeshaft, Nicholas G; Malanchini, Margherita et al. (2017) Phenotypic and genetic evidence for a unifactorial structure of spatial abilities. Proc Natl Acad Sci U S A 114:2777-2782
Zabaneh, Delilah; Krapohl, Eva; Simpson, Michael A et al. (2017) Fine mapping genetic associations between the HLA region and extremely high intelligence. Sci Rep 7:41182
Smith-Woolley, E; Rimfeld, K; Plomin, R (2017) Weak associations between pubertal development and psychiatric and behavioral problems. Transl Psychiatry 7:e1098

Showing the most recent 10 out of 109 publications