The adverse impact of early-onset conduct problems on both the individuals engaging in conduct problems and society makes the examination of the etiology of conduct problems extremely important. The """"""""developmental propensity model"""""""" (Lahey &Waldman, 2003) advances specific and testable hypotheses regarding the etiology of conduct problems, proposing three dimensions of temperament (i.e., negative emotionality, daring, and low prosociality) and low cognitive ability as distinct components of """"""""antisocial propensity"""""""". The proposed study will test the developmental propensity model and alternative hypotheses Keenan &Shaw, 2003;Nigg &Huang-Pollock, 2003), examining very early predictors of early-onset conduct problems and related disruptive behavior disorders. Specifically, the proposed study will: 1) Examine the bur components of """"""""antisocial propensity"""""""" as early predictors of early-onset conduct problems and related disruptive behavior disorders, 2) Test specific hypotheses regarding sex differences in conduct problems, 3) Examine the genetic influences on antisocial propensity and conduct problems, 4) Examine the influence of negative parenting/family environment on conduct problems, and 5) Test specific hypotheses regarding comorbidity in conduct problems. To achieve the above aims, the proposed study will examine existing data from the Colorado Longitudinal Twin Study (LTS), a unique resource of 410 pairs of monozygotic and dizygotic same-sex twins who have been assessed since age 14 months. The LTS affords an exceptional opportunity to test the developmental propensity model, given its longitudinal, genetically informative data. Data analyses being proposed will focus on: a) parenting ratings, teacher ratings, and observational measures of antisocial propensity collected from age 14 months to 7 years, b) parent and teacher ratings of conduct problems from age 4 to 12, c) self ratings of conduct problems collected at age 12, and d) self ratings of conduct problems collected at age 16-19. A substantial amount of work remains in order to make full use of the great potential of the LTS dataset for testing the above specific aims. The proposed study will a) transfer approximately 20,000 hours of observational data from videotapes to DVDs, b) complete the coding of more than 10,000 observational tests of antisocial propensity and parenting, c) systematically review all existing coding for completeness and accuracy of data entry, and d) integrate the newly coded data and the existing data. The proposed study will provide the first comprehensive test of disconfirmable hypotheses from the developmental propensity model for the etiology of antisocial behavior in a genetically informative, multivariate, longitudinal study. As such, the proposed research will permit critical tests of hypotheses derived from the model, and thereby provide important new knowledge regarding the etiology of antisocial behavior, an issue of considerable societal and clinical significance.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD050346-04
Application #
7878874
Study Section
Psychosocial Development, Risk and Prevention Study Section (PDRP)
Program Officer
Maholmes, Valerie
Project Start
2007-09-01
Project End
2012-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
4
Fiscal Year
2010
Total Cost
$304,542
Indirect Cost
Name
University of Colorado at Boulder
Department
Genetics
Type
Other Domestic Higher Education
DUNS #
007431505
City
Boulder
State
CO
Country
United States
Zip Code
80309
Rhee, Soo Hyun; Friedman, Naomi P; Smith Watts, Ashley K et al. (2018) The Association Between Toddlerhood Self-Control and Later Externalizing Problems. Behav Genet 48:125-134
Smith Watts, Ashley K; Friedman, Naomi P; Corley, Robin P et al. (2018) A Longitudinal and Multidimensional Examination of the Associations Between Temperament and Self-Restraint During Toddlerhood. Child Dev :
Woodward, Kerri E; Boeldt, Debra L; Corley, Robin P et al. (2018) Correlates of Positive Parenting Behaviors. Behav Genet :
Rhee, Soo Hyun; Friedman, Naomi P; Corley, Robin P et al. (2016) An examination of the developmental propensity model of conduct problems. J Abnorm Psychol 125:550-64
Johnson, Daniel P; Rhee, Soo Hyun; Friedman, Naomi P et al. (2016) A Twin Study Examining Rumination as a Transdiagnostic Correlate of Psychopathology. Clin Psychol Sci 4:971-987
Rhee, Soo Hyun; Lahey, Benjamin B; Waldman, Irwin D (2015) Comorbidity Among Dimensions of Childhood Psychopathology: Converging Evidence from Behavior Genetics. Child Dev Perspect 9:26-31
Yoo, Yeon Soo; Adamsons, Kari L; Robinson, JoAnn L et al. (2015) Longitudinal Influence of Paternal Distress on Children's Representations of Fathers, Family Cohesion, and Family Conflict. J Child Fam Stud 24:591-607
Yoo, Yeon Soo; Popp, Jill; Robinson, JoAnn (2014) Maternal distress influences young children's family representations through maternal view of child behavior and parent-child interactions. Child Psychiatry Hum Dev 45:52-64
Smith Watts, Ashley K; Patel, Deepika; Corley, Robin P et al. (2014) Testing alternative hypotheses regarding the association between behavioral inhibition and language development in toddlerhood. Child Dev 85:1569-85
Rhee, Soo Hyun; Friedman, Naomi P; Boeldt, Debra L et al. (2013) Early concern and disregard for others as predictors of antisocial behavior. J Child Psychol Psychiatry 54:157-66

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